Bone Abstracts

Nutrition is a major modifiable factor that affects bone health. Dietary potassium may act as an alkaline source by neutralizing the acid load and reducing calcium loss from bone.We aimed to evaluate the association between dietary potassium intake and bone mineral density (BMD) in the Korean population. We analyzed data from the Korean National Health and Nutrition Examination Survey (KNHANES) A total of 3135 men aged >50 years and 4052 postmenopaus...

Low body mass index (BMI) or body weight is a well-known risk factor for osteoporosis and fragility fractures. However, the relative contribution of lean mass and fat mass on bone health, i.e. fragility fractures is inconclusive.We elucidated the relative contribution of lean and fat mass on fracture risk by group analysis in Korean men and women. This was an ongoing prospective community-dwelling cohort study at Ansung in Korea, begun in 2001. We includ...

The pediatric osteogenesis imperfecta (OI) team at our university hospital was established in 1991. The multi- and inter-disciplinary team consists of: pediatric neurologist, nurse, nursing assistant, physiotherapist, occupational therapist, orthopedic surgeon, orthotist, radiologist, dentist and geneticist. We also have a close collaboration with other specialists.Our assignment is high qualified diagnostics, functional assessments and also individualiz...

The aim of this study was to investigate BMD of affected femur in patients with hemiplegic stroke.Medical records of 153 patients with stroke who admitted a rehabilitation clinic from January 2011 to March 2013 were retrospectively reviewed. We excluded the patients with non-hemiplegia, diseases which can affect the BMD such as diabetes mellitus, thyroid disease and anti-epileptic drugs. We also excluded the patients who did not check both femur BMD. Tot...

Objective: The aim of this study was to assess the association between bone mineral density (BMD) and coronary atherosclerosis in healthy postmenopausal women.Methods: We performed a retrospective review of 252 postmenopausal women who visited the health promotion center for a routine checkup, after excluding participants who had factors affecting BMD and coronary artery disease. BMD of the lumbar spine and proximal femur was evaluated by dual-energy X-r...

Objective: The aim of this study was to assess the relationship between renal function (estimated glomerular filtration rate (eGFR) using Cockcroft–Gault (CG) equation and modification of diet in renal disease (MDRD), respectively), bone mineral density (BMD) and both arterial stiffness in Korean postmenopausal women.Materials and methods: From January 2008 until December 2010, among the person who got medical examinations including bone densitometr...

The receptor activator of NF-kB (RANK) and ITAM-containing adaptors have been identified as essential factors involved in osteoclast formation and bone remodeling, but their mechanisms and interacting factors have not yet been fully identified. Here we report that early estrogen-induced gene 1 (EEIG1), a novel RANK ligand (RANKL)-inducible protein, physically interacts with RANK and further associates with Gab2, PLCg2, and Tec/Btk kinases by RANKL stimulation. Overexpression o...

Tannerella forsythia is a gram-negative, anaerobic, asaccharolytic, fusiform bacterium. The presence of the bacterium is associated with various forms of periodontal disease, including gingivitis, chronic and aggressive periodontitis. The expression of GroEL, a bacterial heat shock protein, increases in stressful conditions such as infection. GroEL is a moonlighting protein that has multiple functions. The aim of this study was to evaluate the effect of T. forsyth...

The purpose of this study is to understand the changes of TBS scores in Asian females by comparing 1990’s and 2010’s DXA images.We have compared the DXA images of 3774 Korean females (age: 20–79) to Japanese (age: 20–79). While Korean DXA images were obtained in 2014 and 2015, Japanese data were obtained in 1996. Participants who have abnormal DXA images or lumbar disease were excluded. TBSiNsight® software (v. 2.1.1, ...

The purpose of this study is to assess the correlation of trabecular bone score (TBS) to variable factors, i.e. sex, age, body size and BMD. Moreover, we want to find variables of correlation coefficient change with aging.We randomly selected 2,906 subjects (1726 female and 1180 male, age range 20’s to 70’s) from several hospitals in Korea. Participants who have abnormal Dual Energy X-ray Absorptiometry (DXA) images or lumbar disease were exclu...