Bone Abstracts

Ancient Egyptians were well known for the art of embalming, performed in the belief that preservation of the body was essential for survival in the afterlife. During the mummification process, internal organs were removed and some of them (lungs, stomach, liver, and intestines) washed, dehydrated with natron, perfumed, and stored in so-called canopic jars, buried with the mummy. Each jar had established contents and its own protective deity. To date, a limited number of studie...

Introduction: The importance of vitamin D in metabolism, bone growth and functioning of many organs and systems (the plejotropic effect) has been broadly discussed in the literature recently. The systemic deficiency of vitamin D connected with the lower sunlight exposure and the decreased diet supply favours to bone mineral density lowering and the bone structure disorganization. More and more often the common vitamin deficiency in children and adolescents has been observed. I...

Autosomal Recessive Osteopetrosis (ARO) presents early in life with extreme sclerosis of the skeleton, reduction of bone marrow spaces, hepatosplenomegaly, cranial nerves compression and severe growth failure. ARO is often lethal and at present the only therapy is HSCT, which should be performed as soon as possible in order to obtain a major benefit. ARO is genetically heterogeneous and delays in clinical diagnosis sometimes occur, due to its rareness and to the presence of co...

Objective: To examine bone mineral density (BMD) at the femoral neck (FN) and lumbar spine (LS) in patients (pts) with early axial spondyloarthritis (axSpA).Methods: 73 pts (33 men and 40 women) with early axSpA were included in this study. Pts fulfilled ASAS criteria. Pts enrolled in the study had inflammatory back pain for < 5 years: mean disease duration 19.9±14.4 months. Mean age 28.3±6.4 years, mean BASDAI 4.1±1.9; mean ASDAS-CRP ...

The aim of this study was to determine morphological and densitometric properties of lumbar vertebrae obtained from male and female silver foxes. Five lumbar vertebrae (L2–L6) were isolated from 1-year-old males (n=5) and females (n=6) and cleaned from remaining soft tissues to determine bone weight and vertebral body length. Quantitative computed tomography (QCT) and SOMATOM EMOTION SIEMENS apparatus (Siemens, Erlangen, Germany) were used to determine t...

Tumour growth and metastatic dissemination are significantly reduced in mice bearing an inactivation of the macrophage-colony stimulating factor (M-CSF) gene, due to angiogenesis impairment. In fact, M-CSF directly induces angiogenesis by increasing vascular endothelial growth factor (VEGF) production. Interleukin 34 (IL34), the M-CSF’s ‘twin’ cytokine, was characterized as a new cytokine promoting the growth, survival and differentiation of the myeloid lineage....

Objectives: Abnormal bone mass is one of the late effects which might affect childhood cancer survivors in their later life. There are a lot of studies assessing bone deficits in patients with blood cancer, however there is little research conducted on solid cancer survivors. The aim of this study was to determine the frequency of low bone mass in analyzed group and to assess the influence of time after the end of treatment.Methods: A cross-sectional stu...

Considering limited information on skeletal system properties in emu (Dromaius novaehollandiae), the aim of this study was to determine morphological and densitometric parameters of tarsometatarsus obtained from adult males (N=6) and females (N=7). The study was performed on birds reared at the Department of Poultry and Ornamental Bird Breeding of Western Pomeranian University of Technology in Szczecin, Poland. Male and female emu were slaughtered to obtain l...

The aim of the study was to evaluate interrelationships between morphometric, densitometric and mechanical properties of femur in ostriches (Struthio camelus). 14-month-old male and female ostriches (N=46) were slaughtered to obtain left femur for analyses. Using quantitative computed tomography (QCT) technique, volumetric bone mineral density (vBMD) of the trabecular (Td) and cortical bone (Cd) were measured. Bone mineral density (BMD) and bone mineral content (BMC) ...

Osteoblasts have a high rate of energy consumption during bone formation and bone protein synthesis. Therefore, it is likely that decreased energy production that accompanies aging, could contribute to reduced osteoblast activity, a critical feature of senile osteoporosis, and that this reduction might be counteracted by favoring energy availability. Cells of the osteoblastic lineage generate 40–80% of the requested energy through fatty acid degradation, thus the modulati...