Searchable abstracts of presentations at key conferences on calcified tissues

ba0006pl1 | (1) | ICCBH2017

Poster List

Poster No. Category Title Author P002 Bone development A 3-year longitudinal study of skeletal effects and growth in children after kidney transplantation <a href="ba...

ba0001pp398 | Osteoporosis: treatment | ECTS2013

Health economic consequences of fractures in patients with osteoporosis: a national register based study of total and incremental health costs following fracture

Olsen Kim Rose , Hansen Carrinna , Abrahamsen Bo

Introduction: Osteoporotic fractures are known to be costly to society but estimates tend to be based on small scale prospective studies. In the following we report national data for healthcare costs due to fractures in patients with osteoporosis.Study population and methods: All Danish residents aged 35+, mean age 70.5 years, 13% men, 27.3% prior major osteoporotic fracture, who began bisphosphonates for osteoporosis between 1/1997 and 12/2002 (n</e...

ba0003oc4.6 | Genetics of bone disease | ECTS2014

Gout is associated with an excess risk of osteoporotic fracture: findings from a Danish registry

Dennison Elaine , Rubin Katrine H , Harvey Nick , Walker-Bone Karen E , Schwarz Peter , Cooper Cyrus , Abrahamsen Bo

Objective: Although metabolic syndrome is common in gout patients, recent reports that bone mineral density may actually be reduced (and falls common) in this group have led researchers to hypothesise that osteoporotic fracture may be more common in subjects with gout than in healthy controls. We tested this hypothesis in a national Danish registry.Material and Methods: We identified subjects as new users of allopurinol, a proxy for gout, for the years 1...

ba0003pp333 | Osteoporosis: treatment | ECTS2014

Patients with atypical femoral fractures: characteristics, anabolic treatment and long term follow-up

Tripto-Shkolnik Liana , Jaffe Anat

Background: Atypical fractures (AF) of femoral shaft have distinct radiologic features and are probably related to prolonged bisphosphonate (BP) exposure. They are currently considered to be insufficiency fractures occurring in osteoporotic bone. After initial damage, the repair process calls for accelerated remodeling, but the later is prevented by BP accumulation on the remodeling site. Thus, the fracture expands instead of healing. The management is not postulated, but anab...

ba0004p182 | (1) | ICCBH2015

A case of moderate osteogenesis imperfecta with cerebral palsy spastic quadriplegia; an impossible combination, or is it?

Knowles Elizabeth

A 29 week pre-term female infant, Molly (not real name), was referred to our multi-disciplinary Metabolic Bone Disease Service at the age of 19 months, with a combined diagnosis of inherited osteogenesis imperfecta (OI) and cerebral palsy (CP) spastic quadriplegia, resulting from a intra-ventricular haemorrhage at 7 weeks-old.Diagnosis of OI was confirmed at birth following fractures. Molly was treated with IV Pamidronate from the age of 6 weeks at a loc...

ba0005p129 | Cancer and bone: basic, translational and clinical | ECTS2016

Vertebral fractures among breast cancer survivors in China

Hsieh Evelyn , Wang Qin , Zhang Renzhi , Niu Xin , Li Jing , Zhou Chunwu , Qiao Youlin , Xia Weibo , Fraenkel Liana , Insogna Karl , Smith Jennifer , Zhang Pin

Background: Women with breast cancer (BC) are at high risk for fracture due to the deleterious impact of BC therapies on bone. In China, BC survival is improving as screening and treatment programs expand, however no guidelines exist to prevent BC treatment-induced bone loss. We sought to evaluate the scope of this problem among BC survivors receiving care at a large cancer referral hospital in China.Methods: Women were invited to participate in this cro...

ba0005p295 | Osteoporosis: evaluation and imaging | ECTS2016

Risk factors for subsequent vertebral compression fracture following osteoporotic compression fracture

Soo Kim Sung , Hwan Kim Jin , Hoon Kim Jung , Wan Choi Byung , Hyun Lee Dong

Objectives: To evaluate risk factors of subsequent vertebral fracture following acute osteoporotic vertebral compression fracture.Methods: As a multicenter retrospective study, we recruited 135 patients treated for acute osteoporotic compression fracture with available spine image taken at 1-year follow-up in three hospitals. The patients were divided into two groups according to occurrence of subsequent vertebral fracture. Two groups were analyzed with ...

ba0005p401 | Osteoporosis: treatment | ECTS2016

Two-fold regional variation in initiation of anti-osteoporosis medication after hip fracture in the UK

Shah Anjali , Prieto-Alhambra Daniel , Hawley Samuel , Delmestri Antonella , Lippett Janet , Cooper Cyrus , Judge Andrew , Javaid Kassim

Objective: Describe UK regional variation in prescription of anti-osteoporosis drug therapy before and after a primary hip fracture during 1999–2013.Materials and Methods: We used primary care data (Clinical Practice Research Datalink) to identify patients with a hip fracture and primary-care prescriptions of any anti-osteoporosis drugs (bisphosphonates, strontium, denosumab, oestrogen therapy, SERMS, teriparatide) prior to primary hip fracture and ...

ba0005p424 | Other diseases of bone and mineral metabolism | ECTS2016

Bone mineral density changes in kidney transplant recipients

Smalcelj Ruzica

Bone mineral density (BMD) changes were estimated in kidney recipients. In 63 patients aged 24–64 years, measured creatinine clearance at the end of the first posttransplant year was >50 ml/min and remained stable over the study period, bone mineral density (BMD) was estimated in the lumbar spine, femoral neck, Ward’s triangle and the distal third of the radius using dual energy absorptiometry (DEXA) 0.1–4, 12–18 and 23–36 months after transplantat...

ba0006p138 | (1) | ICCBH2017

Fibrodysplasia ossificans progressiva: baseline characteristics of 101 subjects participating in a global, longitudinal, natural history study

Kaplan Frederick S , Hsiao Edward C , Baujat Genevieve , Brown Matthew A , De Cunto Carmen , Di Rocco Maja , Keen Richard , Al Makkadam Mona , Grogan Donna R , Pignolo Robert J

Objectives: Progressive heterotopic ossification in fibrodysplasia ossificans progressiva (FOP; OMIM #135100) begins in childhood and leads to irreversible restriction of movement, functional impairment, and shortened life-span. Baseline data from an on-going, global, 3-year, natural history study (NHS) describe FOP disease characteristics, and retrospective flare-up history, causes/symptoms, and outcomes.Methods: Data from 101 subjects (recruited from 2...