Bone Abstracts

Objective: To investigate the relationship of frailty with vitamin D in community dwelling elderly women.Materials and methods: A retrospective cross-sectional study was performed on women over 60 years who were not using vitamin D supplementations. Frailty status was defined using Fried’s criteria: weakness, low walking speed, low physical activity, weight loss, exhaustion. Participants were classified as robust, prefrail and frail if they scored 0...

Objective: To assess the incidence and distribution of hip fractures by sex and age among individuals over 40 years in Lithuania in 2010.Materials and methods: This population-based study was performed collecting the data from all orthopaedic-traumatology inpatient departments in Lithuania. The case histories of Lithuanian residents over 40 years, who had suffered a hip fracture in 2010, were examined. Subjects with primary hip fracture (ICD-10 codes S72...

The femoral neck fractures (FNF) are one of the most common non-traumatic fractures in elderly people. Frequently the patients with fractures of this localization need surgical treatment and long-term rehabilitation. It’s widely known that FNF in patients with rheumatoid arthritis (RA) occur more often than in the population.Background: To determine the frequency of FNF in patients with RA and to characterize the patients with RA and with FNF at the...

Objective: Of this study was to investigate the factors influencing fractures in endogenous Cushing’s syndrome (CS) of various etiologies.Materials and methods: The retrospective data of patients, who had received treatment due to endogenous CS, (2001–2011 years) was evaluated. All enrolled patients underwent standard spinal radiographs in lateral positions of the vertebrae Th4-L4. Recent low traumatic non-vertebral fractures were recorded in t...

Objective: To examine the impact on growth and bone mineral density (BMD) of tyrosine kinase inhibitors (TKI) vs hematopoeitic cell transplant (HCT) for treatment of chronic myelogenous leukemia (CML) in patients <18 years of age.Methods: We performed a retrospective review of children with CML in chronic phase treated between 1992 and 2011 at a single institution and evaluated available growth and BMD data.Results: Twenty-five...

Apart from analyses of well-known correlates of age-related hip fracture risk, such as low BMD, impaired external geometry and deteriorated micro-architecture, there is increasing interest to elucidate nano-structural determinants of fracture risk at the bone mineralized matrix level.In this study we analyzed cortical bone specimens of the femoral neck region in five elderly women who sustained hip fracture and in four healthy women of corresponding age....

Tooth fracture is considered as a major problem in dentistry. As it is commonly observed in dental practice, one of the main factors that lead to increased tooth fragility is its devitalization. However, there is no definite mechanistic explanation for such phenomenon. We hypothesize that the possible response to this matter lies in the changes that occur in dentin due to altered microenvironment after endodontic procedure. Therefore, in this study we analyzed the structural a...

In sharp contrast to the great interest in morphology of the proximal femur in aged individuals, there is a paucity of studies in children. To date, a comprehensive quantitative analysis of trabecular micro-architecture in various biomechanically relevant subregions of the immature proximal femur has been lacking. The aim of this study was to characterize postnatal development of trabecular bone in various regions of the human proximal femur. The study sample was comprised of ...

Habitual physical activities of past populations are frequently reconstructed based on musculoskeletal markers (MSM) in human skeletal remains, i.e. particular morphological features of muscles attachment sites. However, the relationship between muscular activity and bone microstructure at the site of muscle attachments is unexplored. Therefore, this study aimed at analyzing bone microstructural characteristics of the muscles attachments sites and correlating these features wi...

Hepatic osteodystrophy is an important complication of chronic liver disease associated with fractures resulting in pain, deformity and immobility. The aim of the study was to examine association of severity of alcoholic liver cirrhosis with areal bone mineral density (BMD) and to estimate bone geometric strength of the proximal femur in those patinets. The study included 27 male patients with alcoholic liver cirrhosis and control group of 36 healthy patients. Laboratory testi...