Searchable abstracts of presentations at key conferences on calcified tissues

Bone Abstracts

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ba0002p158 | (1) | ICCBH2013

Exploring vertebral abnormalities in patients with thalassemia and sickle cell disease

Fung Ellen , Reget Katie , Sawyer Aenor , Haines Drucilla , Lal Ashutosh

Low bone mass is common in thalassemia (Thal) and sickle cell disease (SCD). Bone pain is also reported, though its relationship to low bone mass has not been explored. The aims of this study were to determine the prevalence of vertebral height abnormalities (VHA) and evaluate the relationship between VHA, low bone mass and patient assessed pain in Thal and SCD. Data were collected from the Thalassemia Clinical Research Network Pain Survey study and CHRCO Clinical Bone Density...
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ba0006pl1 | (1) | ICCBH2017

Poster List

Poster No. Category Title Author P002 Bone development A 3-year longitudinal study of skeletal effects and growth in children after kidney transplantation <a href="ba...
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ba0003pp411 | Paediatric bone disease | ECTS2014

Tricho-rhino-phalangeal syndrome TRPS: the new three cases from Poland

Matusik Pawel , Forys-Dworniczak Elzbieta , Kalina-Faska Barbara , Januszek-Trzciakowska Aleksandra , Malecka-Tendera Ewa

Tricho-rhino-pharyngeal syndrome (TRPS) is a rare genetic disorder, which is characterized by craniofacial and skeletal abnormalities. This report presents three cases of TRPS (two sporadic and one familial). Clinical presentation included typical facial features (pear-shape nose, long flat philtrum, thin upper vermilion border and protruding ears), thin, sparse scalp hair and different skeletal abnormalities with normal mentation. Case 1: 5.5-year-old boy with short stature (...
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ba0001pp176 | Cell biology: osteoblasts and bone formation | ECTS2013

The effect of fibroblast growth factor 2 on mesenchymal stromal cell differentiation

Kahkonen Tiina , Ivaska Kaisa K , Harkonen Pirkko

Mesenchymal stromal cells (MSC) have a potential to differentiate to osteoblasts and adipocytes. Differentiation can be stimulated or inhibited by different growth factors, including fibroblast growth factors (FGFs). In this study we evaluated the effect of FGF2 on the osteoblastic and adipocytic differentiation of MSCs in vitro.Mouse MSC-derived cells were cultured in differentiation medium that led to differentiation to osteoblasts in 14 days ...
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ba0004p165 | (1) | ICCBH2015

Clinical masks of the tricho-rhino-phalangeal syndrome: based on the series of four cases from Poland

Matusik Pawel , Forys-Dworniczak Elzbieta , Kalina-Faska Barbara , Januszek-Trzciakowska Aleksandra , Malecka-Tendera Ewa

Background: Tricho-rhino-pharyngeal syndrome (TRPS) is a rare genetic disorder, which is characterized by craniofacial and skeletal abnormalities. Presenting problem: This report presents four cases of TRPS (three sporadic and one familial). Clinical presentation included typical facial features (pear-shape nose, long flat philtrum, thin upper vermilion border, and protruding ears), thin, sparse scalp hair, and different skeletal abnormalities with normal mentation. All of the...
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ba0007p52 | (1) | ICCBH2019

Variable familial expression of spondylometaphyseal dysplasia with coxa vara and a novel FN1 mutation

Steichen-Gersdorf Elisabeth , Biedermann Rainer , Wansch Juergen , Witsch-Baumgartner Martina

Background: Spondylometaphyseal dysplasias (SMDs) comprise a diverse group of skeletal dysplasias and often manifest as short stature, growth-plate irregularities, and vertebral anomalies. One such condition is SMD with ‘corner fractures’ (OMIM #184255). These individuals generally show development of coxa vara, scoliosis and triangular ossification centers at the edges of metaphyses that simulate fractures.Presenting problem: To date only 16 p...
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ba0001pp340 | Osteoporosis: evaluation and imaging | ECTS2013

Trabecular bone score and bone mineral density of lumbar spine in healthy women: pros and cons

Povoroznyuk Vladyslav , Lamy O , Dzerovych Nataliia , Hans Didier

Areal bone mineral density (aBMD) of the PA spine and proximal femur remained the gold standard for WHO classification of osteoporosis, fracture prediction and patient monitoring. Unfortunately, with age it is not infrequent to observe the presence of degenerative disease such as spinal osteoarthritis which would have a positive artifactual impact on aBMD which could lead to an erroneous interpretation. In a previous study it has been demonstrated that apparently such artifact...
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ba0006p104 | (1) | ICCBH2017

Dietary calcium deficiency contributes to the causation of nutritional rickets (NR) in the United Kingdom (UK): data from the British Paediatric Surveillance Unit (BPSU) NR survey

Zulf Mughal M. , Calder Alistair , Blair Mitch , Julies Priscilla , Pall Karina , Lynn Richard , McDonnell Ciara , McDevitt Helen , Shaw Nick J.

Background: Rickets is a disorder of the growing child arising from impaired mineralisation of the growth plate and osteoid. The most common cause of NR in the UK is thought to be secondary to vitamin D deficiency [VDD; serum 25-hydroxyvitamin D (25OHD) <25 nmol/l], although in some African & South Asian countries dietary calcium deficiency (DCaD) by itself, or together with VDD is an important cause of NR (Ann Trop Paediatr. 2006;26:1–16). Currently, the data on ...
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ba0001oc2.3 | Bone quality and fracture repair - animal models | ECTS2013

Low-magnitude high-frequency vibration improves fracture healing in aged, ovariectomized mice

Wehrle Esther , Bindl Ronny , Wehner Tim , Heilmann Aline , Fischer Lena , Noland Jarrod , Amling Michael , Ignatius Anita

Introduction: Fracture healing is impaired in aged and osteoporotic patients. Because bone formation is tightly regulated by the mechanical conditions in the fracture gap and because suitable mechanical stimuli improve fracture healing (Claes et al. 1998), we investigated whether low-magnitude high-frequency vibration (LMHFV; Rubin et al. 2004) is able to improve delayed fracture healing induced by age and ovariectomy in mice.Sudy desig...
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ba0002p137 | (1) | ICCBH2013

Influence of nutritional status in the bone mass assessed by phalangeal quantitative ultrasound of girls aged 7–10 years old

Bertapelli Fabio , Goncalves Ezequiel M , Barbeta Vinicius J O , Krahenbuhl Tathyane , Ramalho Luis C B , Martin Juan E Samur-San , Ribeiro Roberto R , Guerra-Junior Gil

The childhood obesity is a global epidemic. Some studies with pre-pubertal children reported a positive relationship between fat mass and bone. However, there are no available data on the influence of the nutritional status on parameters of quantitative ultrasound (QUS). The aim of this study was to evaluate the influence of nutritional status in bone mass assessed by QUS of proximal phalanges in girls. The bone mass parameter, amplitude dependent speed sound (AD-SoS) in meter...
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Bone Abstracts
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