Searchable abstracts of presentations at key conferences on calcified tissues

Bone Abstracts

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ba0006p020 | (1) | ICCBH2017

Age at onset of walking affects bone mineral content in early childhood

Valkama Saara , Viljakainen Heli , Holmlund-Suila Elisa , Rosendahl Jenni , Hauta-alus Helena , Enlund-Cerullo Maria , Helve Otto , Andersson Sture , Makitie Outi

Objectives: The aim of this study was to evaluate the association between the age at onset of walking and bone mineral content (BMC) in healthy 2-year-old children participating in the Vitamin D in Infants Trial (VIDI).Methods: Altogether 253 children (120 girls, 133 boys) with a daily vitamin D3 intake of 10 μg and a sufficient serum 25-hydroxyvitamin D (25-OHD) concentration (>50 nmol/l) were included in the analysis. BMC was measur...
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ba0006p027 | (1) | ICCBH2017

Sex and iron modify fibroblast growth factor 23 concentrations in 1-year-old children

Holmlund-Suila Elisa , Enlund-Cerullo Maria , Valkama Saara , Hauta-alus Helena , Rosendahl Jenni , Helve Otto , Viljakainen Heli , Andersson Sture , Makitie Outi

Objectives: The regulation of fibroblast growth factor 23 (FGF23) metabolism during infancy is inadequately characterized. We previously observed a distinct sex difference in intact FGF23 at 3 months of age. In this study we aimed to further examine the role of sex and iron status in FGF23 metabolism in 1-year-old children.Methods: This was a cross-sectional study including 731 1-year-old Caucasian children participating the Vitamin D intervention in inf...
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ba0006p095 | (1) | ICCBH2017

Legg Calve Perthes disease and growth hormone treatment

Belceanu Alina Daniela , Armasu Ioana , Tirnovan Mirela , Bursuc Anamaria , Cabac Mariana , Crumpei Iulia , Constantinescu Georgiana , Preda Cristina , Ungureanu Maria Christina , Vulpoi Carmen

Background: Current extension in the usage of growth hormone therapy (GHT) has increased the prevalence of bone complications. Legg Calvé Perthes disease (LCPD) is characterized by idiopathic avascular necrosis of the proximal femoral epiphysis. More frequently in boys between 4 and 8 years, LCPD is of unknown ethology. An increased incidence has been stated in case of GH deficiency. There is increasing data that children with LCPD may have a more widespread skeletal diso...
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ba0006p155 | (1) | ICCBH2017

Dietary protein is associated with bone adaptations and performance of pre-adolescents

Stampoulis Theodoros , Leontsini Diamanda , Avloniti Alexandra , Draganidis Dimitrios , Chatzinikolaou Athanasios , Venetsanou Fotini , Deli Chariklia , Vlachopoulos Dimitris , Gracia-Marco Luis , Michalopoulou Maria , Jamurtas Athanasios , Fatouros Ioannis , Kambas Antonis

Objectives: Nutrition in childhood is a major factor for healthy living during adulthood. Bone mass is influenced immensely by nutritional intake, especially protein intake which is very important for bone matrix and the integrity of skeletal structure. This study aimed to identify the effects of dietary protein intake on bone mineral density (BMD), bone mineral content (BMC) and performance of children aged 6–12 years old.Methods: A repeated measur...
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ba0006p190 | (1) | ICCBH2017

Development of an in vitro model of cancer stem cells from a rare human telangiectatic osteosarcoma

Palmini Gaia , Zonefrati Roberto , Romagnoli Cecilia , Aldinucci Alessandra , Galli Gianna , Mavilia Carmelo , Leoncini Gigliola , Simoni Antonella , Franchi Alessandro , Campanacci Domenico Andrea , Capanna Rodolfo , Brandi Maria Luisa

Objective: Even though recent studies have proved the presence of cancer stem cells (CSCs) in osteosarcoma (OSA), with this study, for the first time, the existence of CSCs in a rare high grade type of OSA, the telangiectatic osteogenic sarcoma (TOS), is showed.Methods: TOS sample was collected at the ‘Ortopedia Oncologica e Ricostruttiva Unit’, AOU Careggi, Florence, with informed consent approved by the local Ethical Committee. First of all, ...
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ba0007p113 | (1) | ICCBH2019

Next-generation sequence and biomarker levels in the patients with early-onset chronic non-bacterial osteomyelitis from North Caucasian region of Russia

Kostik Mikhail , Makhova Maria , Suspitsin Evgeny , Sokolenko Anna , Zorin Vyacheslav , Isupova Eugenia , Magomedova Shamai , Kostik Inna , Takayanagi Hiroshi , Mushkin Alexander , Imyanitov Evgeny

Objectives: Chronic non-bacterial osteomyelitis (CNO) is a heterogenic group of immune-mediated inflammatory bone diseases with unclear pathogenesis. Only a few genes associated with this condition have identified. The aim of the study was to evaluate the spectrum of mutations in genes associated with primary immunodeficiency syndromes (PIDs) and autoinflammatory diseases (AIDs) in the cohort of patients with early-onset CNO from North Caucasus (Dagestan and Chechnya) and asse...
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ba0007lb10 | (1) | ICCBH2019

Foramen magnum stenosis (FMS): neuroradiological aspects before and after cervical decompression in paediatric patients with achondroplasia (ACH)

Allegri Anna Elsa Maria , Di Iorgi Natascia , Severino Mariasavina , Patti Giuseppa , Siri Giulia , Piatelli Gianluca , Fava Daniela , Napoli Flavia , Michelis Beatrice , Maghnie Mohamad

The identification of markers indicative of pathological FMS plays a pivotal role in the prevention of ACH complications.Objective: Identify key cranio-cervical junction neuroradiological features for the surgical choice and for the decompression outcome.Methods: Out of 191 ACH patients, we selected 24 patients before 4 years of age, who performed a first brain MRI and/or CT. Patients were divided into 2 groups: surgically treated ...
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ba0006pl1 | (1) | ICCBH2017

Poster List

Poster No. Category Title Author P002 Bone development A 3-year longitudinal study of skeletal effects and growth in children after kidney transplantation <a href="ba...
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ba0002is1biog | The fracturing child: epidemiology | ICCBH2013

Bone mass and other determinants of fractures in children and adolescents

Clark Emma

Biographical DetailsI am a Consultant Senior Lecturer in Rheumatology at the University of Bristol, UK. My research area is Musculoskeletal Epidemiology, with a particular interest in the role of bone mass in determining fracture risk in children and adolescents. Other areas of interest are the epidemiology of hypermobility and scoliosis in adolescents, and identification of osteoporotic ...
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ba0001pp123 | Calciotropic and phosphotropic hormones and mineral metabolism | ECTS2013

Vitamin D supplementation during lactation: effect on maternal and offspring's vitamin D status and bone mass–double-blind randomized control trial

Czech-Kowalska Justyna , Jaworski Maciej , Latka-Grot Julita , Bulsiewicz Dorota , Pludowski Pawel , Chazan Bogdan , Pawlus Beata , Wygledowska Grazyna , Zochowska Anna , Kornacka Maria K , Kryskiewicz Edyta , Karczmarewicz Elzbieta , Dobrzanska Anna

Introduction: Optimal vitamin D intake for lactating women remains controversial. We hypothesized that 1200 IU/day (vs 400 IU/day) of vitamin D during breastfeeding will enhance maternal vitamin D status and bone mass.Methods: Healthy mothers after term, singleton delivery were randomized to receive vitamin D3: 1200 IU/day (800+400 IU/day from multivitamins) or 400 IU/day (placebo+400 IU/day from multivitamins) during lactation. Serum 25-hydroxyvitamin D...
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Bone Abstracts
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