Abstract Search

ba0006p013 | (1) | ICCBH2017

Longitudinal evaluation of bone mass, geometry and metabolism in adolescent male athletes. The PRO-BONE study

Swolin-Eide Diana , Hansson Sverker , Magnusson Per , Ronne Maria , Heideman Malene , Schou Anders , Laursen Jens Ole , Wedderkopp Niels , Husby Steffen , Molgaard Christian , Ubago-Guisado Esther , Vlachopoulos Dimitris , de Moraes Augusto Cesar , Torres-Costoso Ana , Wilkinson Kelly , Metcalf Brad , Sanchez-Sanchez Javier , Gallardo Leonor , Gracia-Marco Luis Tseretopoulou Xanthippi , Amin Nadia , Mushtaq Talat , Chaplais Elodie , Naughton Geraldine , Greene David , Duclos Martine , Masurier Julie , Dutheil Frederic , Thivel David , Courteix Daniel , Ubago-Guisado Esther , Vlachopoulos Dimitris , de Moraes Augusto Cesar , Torres-Costoso Ana , Wilkinson Kelly , Metcalf Brad , Sanchez-Sanchez Javier , Gallardo Leonor , Gracia-Marco Luis Cheuk Ka-Yee , Wang Xiaofang , Yu Fiona W P , Tam Elisa M S , Ng Bobby K W , Ghasem-Zadeh Ali , Zebaze Roger , Seeman Ego , Cheng Jack C Y , Lam Tsz-Ping , Kutilek Stepan , Formanova Daniela , Senkerik Marian , Skalova Sylva , Markova Daniela , Langer Jan , Kutilek Stepan , Vracovska Martina , Pikner Richard , Fejfarkova Zlatka , Gracia-Marco Luis Vlachopoulos Dimitris , Ubago-Guisado Esther , Barker Alan R , Fatouros Ioannis G , Avlotini Alexandra , Knapp Karen K , Moreno Luis A , Williams Craig A , Vlachopoulos Dimitris , Barker Alan R , Williams Craig A , Ubago-Guisado Esther , Ortega Francisco B , Ruiz Jonathan R , Moreno Luis A , Fatouros Ioannis G , Avloniti Alexandra , Gracia-Marco Luis

Objectives: Cross-sectional studies show that exercise may have positive effects on bone outcomes in youth. However, there is no evidence from longitudinal studies, which type of sports can induce improvements in bone acquisition in adolescent athletes. Therefore, this study aimed to investigate the longitudinal differences in bone acquisition and bone metabolism between adolescent males participating in osteogenic (football) and non-osteogenic (swimming, cycling) sports compa...

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ba0007lb2 | (1) | ICCBH2019

Lumbar spine quantitative computed tomography (QCT) is a better predictor of vertebral fracture in boys with Duchenne muscular dystrophy (DMD) than either DXA or peripheral QCT

Crabtree Nicola , Machin Michael , Padidela Raja , Kariki Eleni , Hughes Imelda , Shaw Nick , Mughal Zulf

Objectives: Vertebral fractures are common in boys with DMD taking daily corticosteroids. Treatment is usually initiated when vertebral fractures have been identified. However, prophylactic treatment may be possible if reliable risk factors for vertebral fracture can be identified. The aim of this work was to compare the diagnostic accuracy of three different bone strength assessment techniques in a cohort of DMD boys.Methods: Thirty-three boys with DMD ...

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ba0006pl1 | (1) | ICCBH2017

Poster List

Poster No. Category Title Author P002 Bone development A 3-year longitudinal study of skeletal effects and growth in children after kidney transplantation <a href="ba...

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ba0005p297 | Osteoporosis: evaluation and imaging | ECTS2016

Dexamethasone produces both bone-loss and bone-spare effects in OPG^−/− mice

Sheng Zhifeng , Zhang Yan , Zhou Yinhui , Wu Xiyu , Yuan Linqing , Ou Yangna , Liao Eryuan , Zhou Houde

The effects of dexamethasone on trabecular and cortical bone in OPG−/− mice were investigated in present study. Forty 6-month-old C57BL/6J female mice, including wt (n=20) and OPG knockout (OPG−/−, n=20), were randomdly divided into four groups and treated with either sterile normal saline or dexamethasone at 1 mg/kg by intramuscular injection 3 days per week. All mice were sacrificed at 4 weeks after these treatm...

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ba0001pp232 | Cell biology: osteoclasts and bone resorption | ECTS2013

The use of photo-activatable fluorophores to study the turnover of the receptor activator of NFκB receptor in health and disease

Mellis David , Duthie Angela , Clark Susan , Crockett Julie

Familial expansile osteolysis (FEO) is characterised by focal areas of increased bone turnover driven by bone-resorbing osteoclasts. The syndrome is caused by a heterozygous tandem insertion duplication mutation within the signal peptide region of TNFRSF11a (encoding receptor activator of NFκB; RANK). Our recent research has demonstrated that heterotrimeric receptor formation may hold the key to the disease phenotype. We have shown previously that, whilst homozygous overe...

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ba0001pp414 | Osteoporosis: treatment | ECTS2013

Treatment with eldecalcitol (ED-71) and raloxifene combined increases cancellous and cortical bone strength in ovariectomized rats

Sakai Sadaoki , Takeda Satoshi , Shiraishi Ayako , Koike Nobuo , Mihara Masahiko , Endo Koichi

Eldecalcitol (ED-71; ELD), a 2β-hydroxypropyloxy derivative of 1α,25(OH)2D3, was approved to treat osteoporosis in Japan in 2011. Raloxifene (RAL), a selective estrogen receptor modulator, is available to treat or prevent postmenopausal osteoporosis. In this study, we compared the effects of combining ELD and RAL against each monotherapy in osteoporotic rats.Eight-month-old female WistarImamichi rats were ovariectomi...

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ePoster Contact

ba0001pp323 | Osteoporosis: evaluation and imaging | ECTS2013

A new ultrasonic method for diagnosis of osteoporosis on hip and spine

Casciaro Sergio , Conversano Francesco , Casciaro Ernesto , Franchini Roberto , Maria Daniela Renna , Greco Antonio , Quarta Eugenio , Quarta Laura , Muratore Maurizio

Introduction: Currently, the only available method to reliably predict osteoporotic fractures is represented by bone mineral density (BMD) measurements on proximal femur or spine, which require the use of X-rays. Aim of this study is to illustrate working principles and feasibility of a new ultrasound (US) method for bone densitometry and osteoporosis diagnosis applicable on both proximal femur and spine.Methods: A new fully automatic algorithm was devel...

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ba0001pp337 | Osteoporosis: evaluation and imaging | ECTS2013

Dietary calcium and vitamin D intake and serum 25-hydroxyvitamin D and parathyroid hormone levels in healthy elderly Spanish men: the relationship with calcaneal and phalangeal quantitative ultrasound and phalangeal dual energy X-ray absorptiometry

Leal Alejo , Luz Canal-Macias Maria , Fernando Calderon-Garcia Julian , Roncero-Martin Raul , Rodriguez-Dominguez Trinidad , Moran Jose M

Purpose: To evaluate whether calcium and vitamin D intake is associated with 25-hydroxyvitamin D (25(OH)D) and parathyroid hormone (PTH) serum concentrations or is associated with either the phalangeal dual energy X-ray absorptiometry (pDXA) or the quantitative bone ultrasound (QUS) at the phalanges and the calcaneus in independent elderly men from southwestern Spain.Methods: Serum PTH and 25(OH)D were measured in 199 healthy elderly men (mean age: 73.31...

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ba0001pp436 | Osteoporosis: treatment | ECTS2013

Bone mineral density changes in patients with prior fracture suboptimally treated with a bisphosphonate: results from denosumab (DMAb)/ibandronate and DMAb/risedronate trials

Recknor Christopher , Roux Christian , Ho Pei-Ran , Hall Jesse , Bone Henry , Bonnick Sydney , van den Bergh Joop , Ferreira Irene , Wagman Rachel , Brown Jacques P

: In osteoporosis, poor adherence to bisphosphonate (BP) therapy is common, and is associated with poor outcomes and increased treatment costs (Siris 2006; Recker 2005). Although compliance is improved with monthly vs weekly dosing (Reginster 2008), no evidence suggests cycling through BP agents offers therapeutic benefit, assessed by bone mineral density (BMD). In two randomized, open-label studies in postmenopausal women aged ≥55 years previously treated with, but subo...

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ba0002p59 | (1) | ICCBH2013

The rapid effect of vibration on bone formation and resorption in the growing skeleton

Harrison Rachel , Ward Kate , Lee Ellen , Bishop Nick

Background: Mechanical stimulation is thought to be critical for bone anabolic activity. It is unclear how quickly the growing skeleton responds to additional externally-applied mechanical stimuli. We wished to determine the acute effect of a standardised mechanical stimulus to the growing skeleton.Objectives: To determine the acute time course and magnitude of bones response to whole body vibration (WBV) in pre-pubertal boys.<p class="abstext"...

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Bone Abstracts

Longitudinal evaluation of bone mass, geometry and metabolism in adolescent male athletes. The PRO-BONE study

Lumbar spine quantitative computed tomography (QCT) is a better predictor of vertebral fracture in boys with Duchenne muscular dystrophy (DMD) than either DXA or peripheral QCT

Poster List

Dexamethasone produces both bone-loss and bone-spare effects in OPG^−/− mice

The use of photo-activatable fluorophores to study the turnover of the receptor activator of NFκB receptor in health and disease

Treatment with eldecalcitol (ED-71) and raloxifene combined increases cancellous and cortical bone strength in ovariectomized rats

A new ultrasonic method for diagnosis of osteoporosis on hip and spine

Dietary calcium and vitamin D intake and serum 25-hydroxyvitamin D and parathyroid hormone levels in healthy elderly Spanish men: the relationship with calcaneal and phalangeal quantitative ultrasound and phalangeal dual energy X-ray absorptiometry

Bone mineral density changes in patients with prior fracture suboptimally treated with a bisphosphonate: results from denosumab (DMAb)/ibandronate and DMAb/risedronate trials

The rapid effect of vibration on bone formation and resorption in the growing skeleton

BiosciAbstracts