Bone Abstracts

Objectives: To evaluate the effect of hormone therapy on the change of bone mineral density in women who showed early menopause after pelvic radiation therapy for uterine cervical cancer.Materials and methods: Through retrospective chart review, the changes of bone mineral density in 63 women with early menopause after pelvic radiation therapy for uterine cervical cancer were evaluated. After the diagnosis of early menopause which was defined as level of...

Introduction: Low level of estrogen has regarded as a main contributing factor of temporomandibular joint (TMJ) arthritis in young women patients. However, there is lack of evidence about the occurrence of arthritis in knee joint (KJ) related with estrogen deficiency. This study aimed to investigate the effect of estrogen deficiency on the loaded and non-loaded bone area of TMJ or KJ.Method and materials: Total of 28 SD rats were allocated into two group...

Objective: Bone is one of endocrine organ and osteocytes secretes FGF23, Sclerostin and DKK1. FGF23 inhibits renal phosphate reabsorption and suppresses 1-α hydroxylase activity. Calcitriol stimulates FGF23 synthesis in bone. We aimed to determine the effect of single bolus injection of vitamin D on serum FGF23, DKK1 and Sclerostin concentrations in vitamin D-deficient subjects.Design and methods: The study group was composed of placebo group with s...

Introduction: The purpose of this prospective study is to investigate whether bisphosphonate-based anti-osteoporosis medication affects fracture healing and clinical outcomes of conservatively treated osteoporotic spinal fractures (OSFs).Method: A total of 105 patients who were diagnosed with acute OSFs were prospectively enrolled. According to their previous medication history, the patients were allocated into group I (n=39, no history of bisph...

The skeletal effects and new biological effect of Vitamin D are receiving increased attention. However detection methods in 25-hydroxyvitamin D (25(OH) D) measurement are not standardized and variation between laboratories ahd methods has become attractive. This study emphasizes relativity and consistency between ELISA, ESI-LC-MS/MS and electrochemical luminescence analysis which are used widely in China. This study collected 64 cases of blood, and finally obtained good relati...

Purpose: The purpose of this study was to investigate the bony change of mandibular condyle when the originally less-loaded or unloaded surface was subjected to functional loading by the newly designed animal experiment, and to evaluate whether this experiment is adequate for the animal model of condylar resorption due to mechanical loading.Methods: Twelve adult male New Zealand white rabbits were used. Unilateral oblique vertical body osteotomy (UOVBO) ...

Objectives: To evaluate risk factors of subsequent vertebral fracture following acute osteoporotic vertebral compression fracture.Methods: As a multicenter retrospective study, we recruited 135 patients treated for acute osteoporotic compression fracture with available spine image taken at 1-year follow-up in three hospitals. The patients were divided into two groups according to occurrence of subsequent vertebral fracture. Two groups were analyzed with ...

Background: Vitamin D status is associated with bone health. Vitamin D deficiency leads to decreased bone formation and increased bone resorption. 25-hydroxyvitamin D (25(OH) D), parathyroid hormone (PTH) levels in children could affect bone turnover, and in turn, the bone markers should reflect vitamin D condition. In children the relationships among 25(OH) D, PTH and bone turnover markers are remain.Objective: To explore the associations among serum 25...

Purpose: Risk factors for intertrochanteric fracture (IF) severity were not studied thoroughly despite the high failure rate of osteosynthesis. The purpose of this study was to identify the risk factor for each fracture type using AO/OTA classification in elderly female patients who experienced IF.Materials and methods: This retrospective study identified 240 women over 50 years old with an incident IF in whom dual-energy x-ray absorptiometry (DEXA) was ...

Osteoporosis takes the form of porous bone loss which is due to aging, insufficient exercise and unbalanced nutrition and so on. A number of treatments were developed to treat the osteoporosis, which were categorized by pharmacological and non-pharmacological methods. However, it is generally accepted that taking too much pharmacological medication may be harmful to the health. Thus, non-pharmacological treatments are considered as the alternative ways to overcome the side eff...