Searchable abstracts of presentations at key conferences on calcified tissues

ba0007is13 | (1) | ICCBH2019

Craniosynostoses in rare skeletal disorders

Rocco Federico Di

Craniosynostosis, defined as the premature closure of one or more of the cranial sutures, is a rare disease. It can be isolated or associated to some craniofacial syndromes. In some instances the craniosynostosis can be secondary to specific skeletal disorders such as hypophosphatemic rickets, hypophosphatasia, achondroplasia, mucopolysaccharidosis, osteopetrosis etc. In this evenience, the consequences of the craniosynostosis can be extremely variable depending on the underly...

ba0006p022 | (1) | ICCBH2017

Bone densitometric parameters and body composition in preterm and term infants at the age of forty weeks of gestational age

Di Iorgi Natascia , Diana Paola

Backgound: Limited data are available on body composition of preterm compared to born at term infants. The aim of our study was to compare bone mass, fat mass-FM and free fat mass-FFM in preterm and term infants at 40th weeks of gestational age (GA).Methods: Thirty-four preterm infants (14M, 20F) born at 31.0±2.2 weeks of GA (range 26–36+3 weeks) and n=8 term neonates (4M, 4F) born at 39.7±1.0 weeks of GA underwent a to...

ba0002p45 | (1) | ICCBH2013

Bone mineral density impairment in marfan syndrome: a hidden and neglected issue

Trifiro Giuliana , Marelli Susan , Mora Stefano , Pini Alessandro

Objectives: Marfan syndrome (MFS) is a connective disorder caused by mutations in FBN1 gene which encodes the extracellular matrix protein fibrillin 1. Pathogenesis relies on a dysregulation of activated TGF-β. Cardiovascular, ocular and skeletal systems are involved with a variable expressivity. Findings evolve with age, making the diagnosis in children more difficult. Skeletal involvement includes disproportionate long bone overgrowth, scoliosis, and chest deformity. Al...

ba0005p293 | Osteoporosis: evaluation and imaging | ECTS2016

DXA in clinical practice: invest in quality to improve accuracy and clinical relevance

Cagnoni Carlo , Gandolfi Stefano , Bibbo Patrizia , Iofrida Mariana , Occhipinti Maria

Introduction: Dual X-ray Absorptiometry (DXA) is currently the best technique available to evaluate bone mass, enabling the diagnosis of osteoporosis, the prediction of fracture risk and monitoring.Clinical good practices consider as preferred measuring sites the lumbar (L1–L4) and proximal femur (neck and total). The vertebral morphometry is a quantitative method for the diagnosis of vertebral fractures based on measuring vertebral heights.<p...

ba0007p96 | (1) | ICCBH2019

Radiofrequency echographic multispectrometry (REMS): a new approach for osteoporosis diagnosis in adolescents

Caffarelli Carla , Pitinca Maria Dea Tomai , Nuti Ranuccio , Gonnelli Stefano

Objective: Dual-energy X-ray absorptiometry (DXA) is the most commonly used method for evaluating bone mineral density (BMD) in children and adolescents. An innovative echographic approach for osteoporosis diagnosis, directly applicable on both femoral neck and lumbar spine, has been recently introduced and clinically validated through single-center and multicenter studies in a adult population. This developed approach has been subsequently defined as Radiofrequency Echographi...

ba0006pl1 | (1) | ICCBH2017

Poster List

Poster No. Category Title Author P002 Bone development A 3-year longitudinal study of skeletal effects and growth in children after kidney transplantation <a href="ba...

ba0001pp325 | Osteoporosis: evaluation and imaging | ECTS2013

Relationship between quantitative ultrasound parameters at calcaneous and health-related quality of life domains in postmenopausal Italian women: the FEDRO study

Gonnelli Stefano , Caffarelli Carla , Guglielmi Giuseppe , Rossi Stefania , Adami Silvano , Nuti Ranuccio

Reduced bone mineral density (BMD) has been reported to adversely affect health related quality of life (HRQoL) also in postmenopausal women without vertebral fracture. To date no data exist in literature about any possible influences of quantitative ultrasonography (QUS) on HRQoL. This study aimed to assess whether QUS parameters at calcaneous may be associated with HRQoL.In 1812 ambulatory postmenopausal women aged 60 years or over, referred by their f...

ba0001pp410 | Osteoporosis: treatment | ECTS2013

Bone turnover markers and radiographic progression of vertebral compression fractures during anti-osteoporotic therapy

Corradini Costantino , Macchi Vittorio , Pasqualotto Stefano , Boisio Francesca , Tradati Daniele , Crapanzano Calogero , Verdoia Cesare

Introduction: In postmenopausal women with vertebral compression fractures (VCF) the mechanisms regulating healing processes and an anti-osteoporotic treatment are not completely clarified. The aim of this prospective study was the evaluation of bone turnover markers, bone mineral density and radiographic progression of one or more VCF during assumption of risedronate, strontium ranelate or teriparatide.Materials and methods: Women with recent osteoporot...

ba0002oc9 | Biology | ICCBH2013

EPO signaling and hematopoietic expansion as causes of osteoporosis in a thalassemia mouse model

Vogiatzi Maria , Yang Zhiwei , Oikonomidou Rea , Rivella Stefano , Boskey Adele , Ross F Paddy

Thalassemia is a chronic anemia associate with high rates of osteoporosis. To determine how erythropoiesis leads to bone loss in thalassemia, we used the th3/+ thalassemia mouse to study the role of erythropoietin (EPO) and hematopoietic progenitors (HP), since they are both increased in thalassemia.Methods: Bone marrow mesenchymal stem cells (MSCs) cultures and MSC cocultures with various HP from wild type (wt) and th3/+ mice were diff...