Searchable abstracts of presentations at key conferences on calcified tissues

ba0002p28 | (1) | ICCBH2013

Vitamin D insufficiency and its correlation with low bone mass in adolescent idiopathic scoliosis

Lam Tsz Ping , Yu Fish Wing Sze , Mak Queenie Wah Yan , Cheung Franco Tsz Fung , Lee Kwong Man , Ng Bobby Kin Wah , Qin Ling , Cheng Jack Chun Yiu

Objectives: AIS is associated with both low bone mass and elevated serum bone alkaline phosphatase. The greater the latitude of the geographical region, the higher is the prevalence of AIS. These specific features were compatible with the presence of either Vit-D insufficiency or abnormal physiology with Vit-D. It is important to evaluate these potentially treatable conditions regarding their roles in the etiopathogenesis of AIS. The objectives of this case-control study were ...

ba0004oc21 | (1) | ICCBH2015

Maternal vitamin D deficiency alters later skeletal responsiveness to mechanical loading in a model system

Borg Stephanie , Buckley Harriet , Nicholson Kirsty , Skerry Tim , Bishop Nick

Fractures in children are common; prospective cohort studies suggest narrower bones predispose to fracture. Early life events can influence later growth and development. Observational studies suggest children born to mothers with lower vitamin D levels during pregnancy have narrower bones. We investigated the effects of maternal vitamin D deficiency on offspring’s bones’ response to mechanical loading in a model system.C57BL/6 female mice (...

ba0004p146 | (1) | ICCBH2015

Hypovitaminosis D and factors associated in healthy children aged 2--14 years old in Mexico

Chico-Barba Gabriela , Huitron Gerardo , Guagnelli Miguel , Clark Patricia

Objectives: To estimate the status of 25-hydroxyvitamin D in healthy Mexican children and to describe factors related to vitamin D deficiency.Methods: A cross-sectional study was conducted in children 2–14 years old in Mexico City and Toluca Edo de Mexico. Trained interviewers applied a questionnaire including all relevant demographics, medical history, sun exposure, sunblock use and skin phototype. Morning fasting blood was collected in all subject...

ba0006p163 | (1) | ICCBH2017

Vitamin D insufficiency and inadequate bone mineral status in newcomer immigrant and refugee children in Canada

Vatanparast Hassan , Lane Ginny

Nutrition and physical activity are two main important factors influencing bone mineral mass accumulation during childhood and adolescence. Newcomer immigrant/refugee children are at a high risk of poor nutritional status. Vitamin D deficiency, in particular, and its related diseases is a major concern due to minimal sun exposure in countries in high latitude and limited dietary sources. Using Healthy Immigrant Children (HIC) polite data (n=72), we previously...

ba0007p5 | (1) | ICCBH2019

Response of bone to mechanical stimulation in the offspring of MAVIDOS study mothers in a single centre; the effect of antenatal vitamin D supplementation

Gopal Sujatha , Rigby Alan , Moon Rebecca , Cooper Cyrus , Harvey Nick , Harrison Rachel , Bishop Nick

Background: Preclinical model studies suggest early life vitamin D depletion reduces bone’s response to mechanical loading. The MAVIDOS trial (randomised placebo controlled trial of vitamin D supplementation in pregnancy) reported winter-born infants of mothers receiving vitamin D supplementation had higher bone mass; the earlier Southampton Princess Ann Cohort study linked pregnancy blood vitamin D levels to later bone mass and size. We showed previously that bone respon...

ba0006p104 | (1) | ICCBH2017

Dietary calcium deficiency contributes to the causation of nutritional rickets (NR) in the United Kingdom (UK): data from the British Paediatric Surveillance Unit (BPSU) NR survey

Zulf Mughal M. , Calder Alistair , Blair Mitch , Julies Priscilla , Pall Karina , Lynn Richard , McDonnell Ciara , McDevitt Helen , Shaw Nick J.

Background: Rickets is a disorder of the growing child arising from impaired mineralisation of the growth plate and osteoid. The most common cause of NR in the UK is thought to be secondary to vitamin D deficiency [VDD; serum 25-hydroxyvitamin D (25OHD) <25 nmol/l], although in some African & South Asian countries dietary calcium deficiency (DCaD) by itself, or together with VDD is an important cause of NR (Ann Trop Paediatr. 2006;26:1–16). Currently, the data on ...

ba0003pp402 | Other diseases of bone and mineral metabolism | ECTS2014

Clinical case of a patient with severe tertiary hyperparathyroidism, osteitis fibrosa cystica and osteomalacia as a consequence of severe vitamin D deficiency

Peretokina Elena , Mokrysheva Natalya

Vitamin D (vit D) plays an important role in the regulation of mineral homeostasis. Vit D insufficiency leads to decreased calcium and phosphorous intestinal absorption, parathyroid glands (PG) stimulation with consequent development of secondary hyperparathyroidism (HPT) and bone mineralization defect. We present a clinical case of a patient with tertiary HPT as a consequence of severe vit D deficiency.A clinical case: A woman 59 years old considered he...

ba0001pp116 | Calciotropic and phosphotropic hormones and mineral metabolism | ECTS2013

Effect of high doses of vitamin D on arterial properties, adiponectin, leptin, and glucose homeostasis in type 2 diabetic patients

Shargorodsky Marina

Background and aims: Vitamin D supplementation has the potential to alleviate the cardiovascular damage in diabetic patients. The present study was designed to evaluate long term impact of high doses of vitamin D on arterial properties, glucose homeostasis, adiponectin and leptin in patients with type 2 diabetes mellitus.Methods and results: In randomized, placebo-controlled study 47 diabetic patients were assigned into two groups: Group 1 received oral ...

ba0002p20 | (1) | ICCBH2013

Assessment of vitamin D nutrition status and dietary calcium intake in children 2–5 years of age

Kureel Priyanka , Seth Anju , Singh Ritu , Marwah R K , Aneja Satvinder

Objectives: To assess the vitamin D nutrition status of healthy children in the age group 2–5 years and to assess the daily dietary calcium intake of these children.Methods: A total of 100 healthy children (age group 2–5 years) were studied in this cross sectional study. Dietary calcium and energy intake was estimated using 24 h dietary recall method. Average sun exposure over last 3 days was assessed by calculating u.v. score. Biochemical para...

ba0006p082 | (1) | ICCBH2017

Impact of age, sex, location of injury, physical activity, vitamin D and calcium intake on the injury outcome of wrist and ankle in children

Alshamrani Hassan A , Alloub Hana , Burke Derek , Offiah Amaka C

Objectives: The aim of this study was to assess the impact of age, sex, location of injury, physical activity, dietary intake of calcium and vitamin D on injury outcome in otherwise healthy children.Materials: This study was a cross-sectional prospective study. Children aged 6 to 15 years who presented to the Emergency Department of a single tertiary paediatric referral hospital were recruited. Children were included it they were known not to have underl...