Searchable abstracts of presentations at key conferences on calcified tissues

Bone Abstracts

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ba0001pp155 | Cancer and bone: basic, translational and clinical | ECTS2013

Influence of sex steroids on sclerostin levels in patients with prostate cancer

Munoz-Torres Manuel , Reyes-Garcia Rebeca , Garcia-Fontana Beatriz , Morales-Santana Sonia , Varsavsky Mariela , Maria Dolores Aviles-Perez , Garcia-Martin Antonia

There is increasing evidence for the key role of osteocytes in the regulation of bone remodeling. One of the main products of these cells, sclerostin, inhibits bone formation and may also stimulate bone resorption. To our knowledge, there are few data in prostate cancer (PC) patients especially in patients with hypogonadism related to androgen deprivation therapy (ADT). The aim of this study was to compare serum levels of sclerostin in ADT-treated and untreated PC patients wit...
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ba0001pp335 | Osteoporosis: evaluation and imaging | ECTS2013

Usefulness of bone turnover markers in the evaluation of fracture risk in type 2 diabetes

Rozas-Moreno Pedro , Reyes-Garcia Rebeca , Garcia-Martin Antonia , Lopez-Gallardo Gema , Garcia-Fontana Beatriz , Morales-Santana Sonia , Munoz-Torres Manuel

Introduction: The utility of the determination of bone turnover markers in the evaluation of fracture risk at the patient level is not well-established. In type 2 diabetes (T2DM) there is an increased risk of fractures despite of higher bone mineral density. A recent study shows that a femoral neck T-score of −2.1 in males and −1.9 in females with T2DM present the same fracture risk than subjects without diabetes with a T-score −2.5 (Schwart...
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ba0003pp372 | Other diseases of bone and mineral metabolism | ECTS2014

Comparative effect of Denosumab vs Teriparatide on bone and energy metabolism

Rubio Veronica Avila , Rodriguez Cristina Novo , Fontana Beatriz Garcia , Martin Antonia Garcia , Garcia Rebeca Reyes , Santana Sonia Morales , Torres Manuel Munoz

Recent studies have demonstrated the role of osteocalcin in energy metabolism regulation having a connection between this and bone metabolism. According to this, anti-osteoporotic drugs may exert different effects on energy metabolism. Thereby, our aim is to evaluate the effects of antiresorptive (Denosumab) and osteoanabolic (Teriparatide) drugs that reduce or increase respectively osteocalcin levels, on energy and bone metabolism by assessing of undercarboxilated osteocalcin...
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ba0004is26biog | (1) | ICCBH2015

Duchenne and cerebral palsy

Munns Craig

Biographical DetailsAssociate Professor Craig Munns is a Senior Staff Specialist in Bone and Mineral Medicine and Endocrinology at the Children’s Hospital at Westmead and Conjoint Associate Professor in the Sydney Medical School at the University of Sydney, Australia. Following the completion of his Paediatric and Endocrinology training at The Royal Children’s Hospital, Brisbane...
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ba0006pl1 | (1) | ICCBH2017

Poster List

Poster No. Category Title Author P002 Bone development A 3-year longitudinal study of skeletal effects and growth in children after kidney transplantation <a href="ba...
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ba0001pp193 | Cell biology: osteoblasts and bone formation | ECTS2013

Normal human osteoblast cells exerts an adaptive effect towards moderate hypothermia by retaining bone metabolism and cellular function in vitro

Aisha Mohd Din , Nor-Ashikin Mohamed Noor Khan , Sharaniza Ab. Rahim , Nawawi Hapizah , Kapitonova Marina , Froemming Gabriele Ruth Anisah

Over the years, it has been demonstrated that the ability to maintain body core temperature in older adult’s declines with age. Temperature is a vital physical factor for cell growth and a downshift in core body temperature (<37 °C) might have a direct affect on maintaining bone density or repair fractures. Disruption in any of the cellular processes involved in bone remodelling leads to a net loss of bone mineral density and bone loss. Therefore our study looked...
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ba0005p363 | Osteoporosis: pathophysiology and epidemiology | ECTS2016

Lower FRAX scores but similar femoral neck aBMD in UK dwelling postmenopausal South Asian women as compared with same age Caucasian women

Darling Andrea L , Hart Kathryn H , Lanham-New Susan A

It is unclear as to whether western dwelling South Asian (SA) postmenopausal women have a different fracture risk to that of the native Caucasian (C) population. Moreover, the WHO Fracture Risk Assessment Tool (FRAX) has not been used previously to compare predicted risk of fractures in western dwelling South Asian women with same-age Caucasian women. This analysis used data from n=35 SA [mean (S.D.) age=59 (6) years] and n=136 C [mean (...
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ba0001pp274 | Genetics | ECTS2013

Association between polymorphisms in leptin, its receptor and β adrenergic receptors genes and bone mineral density in postmenopausal Korean women

Kim Hoon , Ku Seung-Yup , Kim Seok Hyun , Choi Young Min , Kim Jong Hak , Kim Jung Gu

Objective: The purpose of this study was to investigate the association between single nucleotide polymorphisms (SNPs) in leptin (LEP), its receptor (LEPR) and β adrenergic receptor (ADRB) genes and bone mineral density (BMD) in postmenopausal Korean women.Methods: The LEP c.280G>A, LEPR c.326A>G, c.668A>G, c.1968G>C, c.2096C>T, ADRB2 c.46A>G, c.79C>G, c.718T>C, c....
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ba0001pp504 | Paediatric bone disease | ECTS2013

The serum levels of carboxylated and undercarboxylated osteocalcin in children with cystic fibrosis

Ambroszkiewicz Jadwiga , Sands Dorota , Gajewska Joanna , Chelchowska Magdalena , Laskowska-Klita Teresa

Introduction: Osteocalcin (OC) is the noncollagenous protein of bone matrix produced by osteoblasts which play an important role in bone metabolism. In its carboxylated form (c-OC) osteocalcin binds to hydroxyapatite in bone and plays a regulatory role in bone formation and mineralization. In contrast, undercarboxylated OC (uc-OC) binds less effectively to hydroxyapatite and a significant association has been found between fracture incidence and uc-OC in elderly subjects. Unde...
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ba0003pp227 | Osteoporosis: evaluation and imaging | ECTS2014

New point of care method for osteoporosis diagnostics in us

Karjalainen Janne , Riekkinen Ossi , Schousboe John

Objective: Currently, majority of the osteoporotic patients are not diagnosed i) a new ultrasound based device (Bindex) has been recently introduced for osteoporosis (OP) screening and diagnostics at primary healthcare ii) Bindex measures cortical thickness and determines parameter called density index (DI). Thresholds for DI in OP assessment have been determined in Finnish-Caucasian (F-C) population (n=448) along the International Society of Clinical Densitometry (IS...
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Bone Abstracts
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