Bone Abstracts

Objectives: To describe the incidence of vertebral fractures in steroid-treated children.Methods: Fractures were assessed prospectively each year for 3 years according to the Genant semi-quantitative method. Proportions of children with incident fractures were determined annually over the study period. To examine associations with baseline clinical factors, the 3-year total number of incident fractures was analyzed using multivariable Poisson regression....

Background: Elevated plasma homocysteine levels are a risk factor for osteoporotic fractures. Supplementation with vitamin B12/folic acid lowers homocysteine levels. This study aimed to determine whether vitamin B12/folic acid supplementation reduces osteoporotic fracture incidence in hyperhomocysteinemic elderly.Methods: B-PROOF is a double-blind, randomized, placebo-controlled trial including 2 919 participants aged ≧65 years with elevated homocyste...

The aim of the study was to evaluate interrelationships between morphometric, densitometric and mechanical properties of mandible in Polish Merino sheep. Males (n=7) were kept to slaughter age of 5 months of life to obtain mandible. After the slaughter, morphological properties of the mandible such as bone weight and length were determined. Using quantitative computed tomography (QCT) technique and Somatom Emotion, Siemens apparatus, volumetric bone mineral density (v...

Objective: Assessment of bone mineral density in children completing therapy for lymphoma.Methods: Thirty-five children treated for childhood Hodgkin and non-Hodgkin lymphoma at the Department of Pediatric Hematology and Oncology of Medical University of Bialystok in Poland were included. Patients were scanned with DXA at two time points: 1st – up to 5 years and 2nd – above 5 years after the completion of the treatment. Bone mineral density (to...

Objective: Assessment of low bone mass in children with acute lymphoblastic leukemia.Methods: A total of 141 patients (83 boys and 57 girls) treated for acute lymphoblastic leukemia at the Department of Pediatric Hematology and Oncology of Medical University of Bialystok in Poland were assessed for low bone mineral density. Depending on age of diagnosis three clinical groups were analyzed: i) up to 5 years old, ii) from 6 to 12 years old, and iii) from 1...

The aim of the study was to evaluate relationships between morphometric, densitometric and mechanical properties of tarsometatarsus in ostriches (Struthio camelus). Males (n=9) and females (n=15) were kept to slaughter age of 14 months of life to obtain left tarsometatarsus. Using computed tomography technique (Somatom Emotion, Siemens), volumetric bone mineral density (vBMD) of the trabecular (Td) and cortical bone (Cd) were measured. Areal BMD and ...

The aim of this study was to determine interrelationships between final body weight, bone-specific alkaline phosphatase (BAP), IGF1 and morphological, densitometric and mechanical properties of deciduous mandibular teeth isolated from seven healthy Polish Merino rams. Four incisors (I1–I4) and second premolar (P2) were obtained from 5-month-old sheep. Teeth were cleaned, weighed, and their length was measured. Mean volumetric tooth mineral...

The aim of the study was to evaluate time-related changes in serum concentration of bone tissue metabolism markers in Polish Large White male pigs. At birth, the piglets were divided into four groups. The first control group (n=7) received physiological saline i.m. (placebo). The second group (NanoCa group; n=7) were administered p.o. with nanopartical calcium (Ace Nano Calcium, NanoTechWorld, Pohang, Korea). The third group (Dex group; n=7) received...

The aim of the study was to evaluate relationships between morphometric, densitometric and mechanical properties of tibiotarsus in ostriches (Struthio camelus). 14-month-old males (N=15) and females (N=31) were slaughter to obtain left tibiotarsus. Using computed tomography technique (Somatom Emotion scaner, Siemens), volumetric bone mineral density (vBMD) of the trabecular (Td) and cortical bone (Cd), mean voulmetric bone mineral density (MvBMD) and...

The aim of the study was to evaluate effects of 6-month-long administration with nanopartical calcium on morphological and densitometric properties of axial skeleton in pigs subjected to osteoporosis induction with dexamethasone. Male newborn piglets (N=28) were divided after birth into four equal groups (control group receiving placebo, Dex group receiving dexamethasone, NanoCa group receiving orally nanopartical calcium and NanoCa/Dex group) receiving simultaneously...