Bone Abstracts

Biographical DetailsFrank RutschFrank Rutsch is a consultant and Associate Professor in Pediatrics at Münster University Children’s Hospital, Münster, Germany. He graduated from Münster University Medical School in 1992 and took part in the Pediatric residency program in Dresden University and Dortmund Municipal Hospital, Germany...

Biographical DetailsLeanne WardDr Leanne Ward is an Associate Professor of Pediatrics at the University of Ottawa where she has held a Research Chair in Pediatric Bone Health since 2010. She is the Medical Director of the Pediatric Bone Health Clinical and Research Programs at the Children’s Hospital of Eastern Ontario. Dr Ward’s research ...

Biographical DetailsDr S Kirmani is an Assistant Professor in Medical Genetics and Pediatrics at Mayo Clinic, Rochester, MN. He received his medical degree from Dow Medical College, University of Karachi, Pakistan. He went to Mayo Clinic to pursue a residency in Pediatric & Adolescent Medicine, and stayed there for a fellowship in Pediatric Endocrinology. He went on to pursue further ...

Biographical DetailsDr Mary Leonard, MD, MSCE is a Professor of Paediatrics and Epidemiology at the Perlman School of Medicine at the University of Pennsylvania, and the Director of the Office of Clinical and Translational Research at the Children’s Hospital of Philadelphia. Her multidisciplinary research program is focused on the assessment of bone health in children, and the detrim...

Biographical DetailsAmaka C Offiah is Senior Lecturer and Consultant Paediatric Radiologist at the University of Sheffield and Sheffield Children’s Hospital. She has a specialist interest in the musculoskeletal system. She has co-authored two books, seven book chapters, published 67 peer-reviewed articles and given over 100 invited national and international lectures. She is Convenor...

Background: Based on our recent data, nutritional status disturbances (both under- and overweight) can be associated with the severity of scoliotic curve. Objectives: The study objective was to compare two methods for the assessment of nutritional status (routine BMI calculation vs body composition analysis by bioelectrical impedance analyzer (BIA)) in the group of pediatric patients with idiopathic scoliosis (IS).Methods: 317 patients (240 girls/77 boys...

Nitrogen-containing bisphosphonates (N-BPs) are used to treat osteolytic bone metastases. N-BPs have been previously shown to enter macrophages via macropinocytosis, but the mechanisms how they are taken up by breast cancer cells are so far incompletely known. In breast cancer primary tumours N-BPs have been shown, by other researchers, to be bound to micro-calcifications present in the tumour stroma. In our study we have characterized how different N-BP formulations, free, ca...

Biographical DetailsJosé Luis MillánProfessor José Luis Millán received his early training in clinical chemistry and biochemistry at the University of Buenos Aires, Argentina, and his PhD in Physiological Chemistry at the University of Umeå, Sweden, in 1983. Professor Millán is currently based at the Children’s Hea...

Biographical DetailsCraig B LangmanProfessor Craig B Langman, is the Isaac A Abt, MD, Professor of Kidney Diseases at the Feinberg School of Medicine, Northwestern University, Head of Kidney Diseases at the Ann and Robert H Lurie Children’s Hospital of Chicago. His research focuses on the basic and clinical expression of inherited or acquired d...

Background: X linked hypophosphataemic rickets is the commonest cause of renal phosphate wasting, however sporadic cases may warrant additional investigations to exclude less common causes, as exemplified by our case.Presenting problem: A 3 year 7 month boy was referred for assessment and ongoing management of rickets and short stature (height less than 1st %.) He originally presented with leg bowing and waddling gait from the age of 12 months...