Bone Abstracts

Background: Osteoporosis is the most common metabolic disease of bone and constitutes one of the most important major public health problems not only in women but also in men. This cross-sectional study examined the association of lifestyle and nutritional factors with bone mineral density (BMD) in 88 Korean middle-aged men.Methods: Physical measurement, smoking habits, alcohol consumption, physical activity and nutritional analysis were assessed from an...

The purpose of this study is to assess the correlation of trabecular bone score (TBS) to variable factors, i.e. sex, age, body size and BMD. Moreover, we want to find variables of correlation coefficient change with aging.We randomly selected 2,906 subjects (1726 female and 1180 male, age range 20’s to 70’s) from several hospitals in Korea. Participants who have abnormal Dual Energy X-ray Absorptiometry (DXA) images or lumbar disease were exclu...

Objective: To investigate the characteristics and related factors of bone mineral density (BMD) in men of different ages with type 2 diabetes.Methods: Four hundred and forty four male patients diagnosed with type 2 diabetes and 208 healthy men were involved from 2013 to 2014. The BMD of all men including lumbar spine (L1–L4), femoral neck, trochanter, and total hip were detected using dual-energy X-ray absorptiometry produced by the US company. We g...

Introduction: Vitamin D deficiency is common in patients with rheumatoid arthritis and may be related to disease activity.The aim of the study was to evaluate the association between 25(OH)D level and disease activity in patients with rheumatoid arthritis.Materials and methods: The study included 61 patients with rheumatoid arthritis, 73.8% were women, 70.4 patients were younger 60 years old. Subjects suffering from liver and kidne...

Introduction: FGF-21 is a protein that is produced by the liver and adipocytes. In patients with anorexia nervosa (AN), it could be involved in a complex adaptive response to starvation. In addition, this newly discovered protein could play pathogenic role in trabecular skeletal homeostasis. The aim of our work was to evaluate the concentrations of FGF-21 and bone metabolism in patients with AN.Methods: Thirty seven female patients (aged 14.76±3.99 ...

Turn your challenges into opportunities through EU funding for research and innovation.The European Union encompasses several funding mechanisms to support research and innovation (R&I). One of its main instruments is Seventh Framework programme (FP7), established for the period 2007–2013, which is now approaching its end.The successor EU instrument, called Horizon 2020 (H2020), is currently under ...

Children with chronic medical conditions are at increased risk for bone fragility from multiple mechanisms, related both to the underlying condition and its treatment, in particular glucocorticoids. The differential effects of the underlying medical disease on bone micro-architecture have not been well elucidated.Objectives: To describe the bone micro-architectural characteristics in children with rheumatic and oncological disorders treated with glucocor...

Purpose: Osteoporosis (OP) aggravates with vasculature degeneration and improvement of vasculature could prevent OP. We, thus, hypothesize that vascular structure and function play an important role in the development of OP. Type 2 diabetes mellitus (T2DM) patients are vulnerable to vasculopathy, so T2DM were involved in this project to study the correlation between vasculopathy and bone mineral density (BMD).Methods: A total of 427 (180 in OP group; 247...

Objectives: Respiratory insufficiency is the leading cause of mortality for individuals diagnosed with Osteogenesis Imperfecta (OI), a skeletal dysplasia clinically characterized by fractures, bone fragility, and scoliosis. The objective of this study is to explore respiratory function and its relation to quality of life, type of OI, presence of scoliosis, stature, and other factors such as age or co-existing co-morbidities.Methods: Adults with OI comple...

Trabecular bone score (TBS) extracts a texture parameter from pixel grey-level variations in DXA lumbar spine images. The TBS is claimed to be a measure of trabecular structure and was validated in an in-vitro study of vertebral bodies with micro-CT1. TBS has shown the potential for fracture pre-diction in adults2. However, data are sparse regarding the reliability and usefulness of TBS3 and the method has not previously been applied i...