Bone Abstracts

Objective: To study any possible relations of vitamin D status and metabolic syndrome (MetS) components in children, since there is evidence for extraskeletal functions of vitamin D, and its deficiency may contribute to the pathogenesis of several major diseases. In addition to explore any possible role of birth weight (BW).Methods: Clinically healthy children aged 3–9 years (n=152) were included in the study. Forty-six were born large for ...

Biographical DetailsCatherine M Gordon, MD, MSc is a Professor of Pediatrics at the Alpert Medical School of Brown University and is Director of the Division of Adolescent Medicine at Hasbro Children’s Hospital. She is board-certified in adolescent medicine and pediatric endocrinology. She is on the Board of Directors for the International Society for Clinical Densitometry, and direc...

Introduction and aims: Vitamin D deficiency is a prevalent disorder in developing countries. Clinical manifestations of the deficiency include musculoskeletal disorders, such as nonspecific muscle pain, poor muscle strength and low bone mineral density (BMD). The aim of this study was to determine the prevalence of vitamin D deficiency and low BMD in healthy Saudi women.Methods: The subjects of this cross-sectional study comprised 449 healthy Saudi women...

Objectives: The aim of this study was to determine the relationship between 25-hydroxyvitamin D (25(OH) D) level and blood pressure (BP) in Saudi women and to assess the effect of BMI, as a measure of adiposity, on this relationship.Methods: Three-hundred and three apparently healthy Saudi women (20–40 years old) were randomly selected for this cross-sectional study. All women signed an informed consent and the study was approved by the Ethical Comm...

Introduction: Vitamin D is essential for calcium metabolism as well as for fracture prevention. It plays a major role in bone health. A high prevalence of inadequacy has been reported in many studies. A serum 25-hydroxy vitamin D level of 30 ng/ml (75 nmol/l) has been proposed as the minimum for adequate vitamin D nutrition. The prevalence of inadequacy in different regions of the world has not been well characterized. The aim of this study was to evaluate and propose new base...

Background: Vitamin D (Vit-D) plays a role in calcium metabolism during pregnancy, and studies have found widespread deficiency in this period. Its significance is still not fully understood, although low Vit-D levels have been associated with increased risk for preeclampsia, bacterial vaginosis, neonatal sepsis and early respiratory infections in the infant. Supplementation to the pregnant mother remains a matter of debate; thus, it is important to better understand the cause...

Objective: To establish the difference between deficiency, insufficiency and normal results of vitamin D according to severity of motor function disorder and the level of bone mineral density in children with cerebral palsy.Methods: Investigation encompassed 23 children, both genders, between 6 and 17 years of age, with diagnosed cerebral palsy, who were hospitalized between January 1 and December 31, 2014. Bone mineral density (BMD) was established usin...

Background: There is currently considerable clinical and academic interest in vitamin D in children and young people. This partly relates to recognition of a resurgence of symptomatic vitamin D deficiency with reports of children presenting with rickets or hypocalcaemic symptoms. An additional development has been the recognition that vitamin D may have a physiological extraskeletal role beyond its traditional function as a key regulator of calcium and bone metabolism.<p c...

Introduction: Low 25-hydroxyvitamin D (25OHD) levels are frequently found in fertile women and associated with low birth weight, reduced fertility and adverse pregnancy outcomes.Objective: We investigated the effects of vitamin D supplementation on birth weight, fertility, and delivery complications in women planning pregnancy with low 25OHD levels.Methods: This was an investigator-initiated double-blind, randomized, placebo-contro...

Background: Vitamin D status is associated with bone health. Vitamin D deficiency leads to decreased bone formation and increased bone resorption. 25-hydroxyvitamin D (25(OH) D), parathyroid hormone (PTH) levels in children could affect bone turnover, and in turn, the bone markers should reflect vitamin D condition. In children the relationships among 25(OH) D, PTH and bone turnover markers are remain.Objective: To explore the associations among serum 25...