Bone Abstracts

The main cause of the bone destruction in rheumatoid arthritis (RA) is a destructive act of aggressively growing pannus, growth and angiogenesis of which are caused by the proliferation of fibroblasts in the synovium (S) due to the activation of fibroblast growth factor (FGF).Objectives: To reveal relationships of FGF with ultrasonic and arthroscopic and proliferative-destructive histological figures in RA.Methods: Complete compreh...

Objective: In children, factors such as age and puberty are confounders when investigating associations of fat or lean with bone mineral content (BMC). Our aim was to assess influence of fat on BMC in overweight/obese (ow/ob) and normal weight (nw) children at different stages of puberty.Methods: Cross-sectionally, 244 children+adolescents (6–16 years) (73nw, 177ow/ob) were assessed (tanner staging (TS), body composition (DXA) (total body BMC, lean ...

Biographical DetailsDr P Dimitri studied Medicine at the University of St Andrew’s in Scotland and the University of Manchester where he received a medal in pathology and a distinction in Paediatrics. In 2010 he was awarded a PhD in Medicine and the Michael Blacow Award from the Royal College of Paediatrics and Child Health for his work on the relationship of fat and bone in children...

Prof. David Little received his Medical Degree from the University of Sydney where he is Conjoint Professor of Paediatrics and Child Health, specialising in Orthopaedic Surgery. Prof. D Little is Head of Orthopaedic Research and Biotechnology at The Children’s Hospital at Westmead, part of the Sydney Children’s Hospital Network. He has broad clinical interests in Children’s Orthopaedi...

Biographical DetailsSandy Burnham received his MD from the Perelman School of Medicine at the University of Pennsylvania (UPENN) in 1997 and completed his Pediatrics Residency in 2000 and General Pediatrics and Pediatric Rheumatology Fellowships in 2004 at The Children’s Hospital of Philadelphia (CHOP). He received his Master of Science in Clinical Epidemiology from UPENN in 2006. Dr...

Paget’s disease of bone is a condition where the process of bone remodeling is disrupted; Its primary event is an increased bone resorption followed by a subsequent reactive bone formation. The disease is most common in central Europe, the United Kingdom, Australia, and New Zealand. It is also found, though with lower incidence, in southern Europe, Scandinavia, and the United States. It is extremely rare in East Asian countries, especially in Korea, Japan, China, the Midd...

Associate Professor Munns is a Senior Staff Specialist in Bone and Mineral Medicine and Endocrinology at the Children’s Hospital at Westmead and Conjoint Associate Professor in the Sydney Medical School at the University of Sydney, Australia. Following the completion of his Paediatric and Endocrinology training at The Royal Children’s Hospital, Brisbane, Australia, Associate Professor Munns was Clinical Associate in Genetic and Metabolic Bone Disor...

Biographical DetailsFrank Rauch trained as a pediatrician at the Children’s Hospital of Cologne University, Germany, where he started working on pediatric bone disorders in Dr Schoenau’s laboratory. He then performed a research fellowship on metabolic bone disorders at the Shriners Hospital for Children, Montreal, Canada. Since 2001 he has been a clinician scientist at the Shrin...

Biographical DetailsDr. Outi Mäkitie received her MD and PhD from the University of Helsinki, Finland where she also completed training in Pediatrics and in Pediatric Endocrinology. After a 3-year post-doctoral clinical and research fellowship at The Hospital for Sick Children in Toronto, Canada, she returned to Finland and served as Head of the Metabolic Bone Clinic, Children’s...

Biographical DetailsKen White, PhD is the David D Weaver Professor of Genetics in the Department of Medical and Molecular Genetics at the Indiana University School of Medicine in Indianapolis, IN, USA. He serves as Director of the Division of Molecular Genetics and Gene Therapy. Dr K White’s research interests focus on the molecular genetics of metabolic bone diseases in regards to p...