Bone Abstracts

Objective: We aim to investigate gender similarities and differences in femoral neck (FN) structure of elderly population by bone investigational tookit (BIT) of quantitative computed tomography (QCT).Material and methods: This cross-sectional study was part of China Action on Spine and Hip Status study, including 207 males aged 55–87 years and 400 females aged 55–96 years. QCT scans were performed in the hip for the subjects, and we used BIT s...

see P296....

Introduction: Femoral neck fractures and trochanteric fractures are two major types of hip fractures. The BMD changing or hip strength analysis (HSA) of the two type fractures may be different. No research had focused on a large sample of Asian people. This study investigated the differences in BMD and morphologic features of the two type hip fractures of elderly Asian people from QCT.Methods: A total of 279 elderly Chinese patients with hip fractures du...

Purpose: PK-VF study, being conducted in 2007–2008 and 2012–2013, was aimed to investigate the prevalence and 5-year incidence of vertebral fractures (VFs) in postmenopausal women aged 50 years or older in Beijing, China.Methods: In the 2007–2008 survey, we randomly selected a community-based population of 1825 postmenopausal women, of whom 952 women also participated in the 2012–2013 survey. Adopting the same sampling strategies as 2...

Purpose: The aim of this 5-year prospective study was to investigate the association between type 2 diabetes mellitus (T2DM) and incident osteoporotic fracture (IOF) in Chinese postmenopausal women aged 50 years or older.Methods: We included 826 subjects, participating in both the baseline (2007–2008) and follow-up (2012–2013) studies. Based on the diagnosis of T2DM, subjects were first individualized into Non-T2DM and T2DM groups, which were t...

Abstract unavailable....

Background: The baby growing in its mother’s womb needs calcium for skeletal development. Maternal osteoporosis has been attributed to pregnancy in some cases.Presenting problem: A 27-year-old woman in the 7th month of her first pregnancy complained of mid-thoracic back pain after lifting a non-heavy object. The pain remained with differing intensity and was attributed to her pregnancy. After the delivery of a healthy child, the back pain prevented ...

Background: Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy in children and it is well known for its progressive deteriorating course. Nowadays, use of glucocorticoids is the gold standard of treatment for this group of patients as it can significantly prolong ambulation, decrease risk of scoliosis, and pulmonary functions. However, the use of glucocorticoid is associated with increased risk of vertebral and lower limb fractures, which could further acc...

Vaspin (visceral adipose tissue-derived serine protease inhibitor) is a newly discovered adipokine that widely participates in diabetes mellitus, polycystic ovarian syndrome and other disorders of metabolism. However, the effect of vaspin on the regulation of osteogenesis and the mechanism responsible are still unclear. Here, we found that vaspin could attenuate the ALP activities, osteocalcin secretion and Runx2 expression in the preosteoblast cell line MC3T3-E1 in a dose-dep...

Objectives: Poor bone health in boys with Duchenne Muscular Dystrophy (DMD) due to muscle weakness and glucocorticoid treatment is a major concern. This study assesses the bone health status in DMD boys with glucocorticoid treatment in a single centre.Methods: A retrospective chart review from January 2009 to January 2017 was undertaken on all DMD cases with active follow-up in a single paediatric unit in a University-affiliated hospital. We assessed the...