Searchable abstracts of presentations at key conferences on calcified tissues

Bone Abstracts

Published by BioScientifica

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ba0004p129 | (1) | ICCBH2015

Cortical area and volumetric density during pubertal growth: longitudinal analysis in black and white South African adolescent males

Schoenbuchner Simon , Ward Kate , Norris Shane , Prentice Ann , Pettifor John

Skeletal development during childhood and adolescence is an important determinant of adult bone health. Patterns of growth differ between populations, but it is unclear how these differences relate to changes in bone size and volumetric density. We aimed to examine ethnic differences in skeletal phenotype in the context of pubertal growth and development in 279 adolescent males from Johannesburg, South Africa.We performed annual peripheral quantitative c...
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ba0006p159 | (1) | ICCBH2017

Maternal calcium supplementation in a rural Gambian population associated with reduced blood pressure among adolescent female, but not male, offspring

Schoenbuchner Simon , Moore Sophie , Jarjou Landing , Ward Kate , Prentice Ann

We have previously observed sex-specific effects of maternal calcium supplementation on offspring childhood growth, in a rural Gambian population with habitually low calcium intake (~300 mg daily).1,2 There was no effect on maternal blood pressure, the primary outcome of the original trial.3 In this study, we aim to investigate effects on offspring blood pressure (BP) in the same cohort. We recruited children (205 female, 182 male) born following a random...
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ba0006p160 | (1) | ICCBH2017

Maternal calcium supplementation in a rural Gambian population associated with reduced height and weight among adolescent female, but not male, offspring

Schoenbuchner Simon , Moore Sophie , Jarjou Landing , Prentice Ann , Ward Kate

We have previously reported sex-specific effects of prepubertal calcium supplementation on the timing of adolescent growth,1 as well as sex-specific effects of maternal calcium supplementation on offspring childhood growth,2,3 in a rural Gambian population with habitually low calcium intake (~300 mg daily). In this study, we aim to investigate longer-term effects of maternal calcium supplementation on adolescent growth in same cohort. We recruited childre...
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ba0002oc16 | Diagnostics | ICCBH2013

Longitudinal analysis of volumetric density, size and strength towards the end of skeletal maturation in Gambian males habituated to low calcium intake

Schoenbuchner Simon , Prentice Ann , Sawo Yankuba , Ceesay Mustapha , Mendy Michael , Ward Kate

To understand differences in bone health between and within populations, it is crucial to characterise bone development during childhood and adolescence. Peak height velocity at age 16 and young adult height at age 23.5 years were recently reported in Gambian males accustomed to low calcium intake1. Our study aims to describe bone accrual after peak height velocity in the same population.We used peripheral quantitative computed tomography to m...
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ba0004p188 | (1) | ICCBH2015

Fractures, bone mass and geometry in black and white South African children: The Birth to Twenty cohort

Thandrayen Kebashni , Schoenbuchner Simon , Ward Kate , Micklesfield Lisa , Norris Shane , Prentice Ann , Pettifor John

The prevalence of fractures in white children in South Africa is double that of black children (1). White males who fractured were shown to be more physically (2). The aim of this study was to compare the bone mass and geometry measures using peripheral quantitative computed tomography (pQCT) and dual energy x-ray absorptiometry (DXA) in black and white children with and without a history of fracture to determine the risk factors for fractures.Lifetime f...
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ba0006pl1 | (1) | ICCBH2017

Poster List

Poster No. Category Title Author P002 Bone development A 3-year longitudinal study of skeletal effects and growth in children after kidney transplantation <a href="ba...
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ba0002p89 | (1) | ICCBH2013

Painful vertebral fractures during pregnancy: be aware of a potentially underlying genetic cause

Zillikens M Carola , Campos-Obando Natalia , Oei Ling , Simon Marleen

Background: The baby growing in its mother’s womb needs calcium for skeletal development. Maternal osteoporosis has been attributed to pregnancy in some cases.Presenting problem: A 27-year-old woman in the 7th month of her first pregnancy complained of mid-thoracic back pain after lifting a non-heavy object. The pain remained with differing intensity and was attributed to her pregnancy. After the delivery of a healthy child, the back pain prevented ...
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ba0006p030 | (1) | ICCBH2017

Outcomes of zoledronic acid use in paediatric conditions

Lim Angelina , Simm Peter , James Simon , Zacharin Margaret

Objectives: Intravenous bisphosphonates have been used in children for various primary and secondary bone fragility disorders for three decades but beyond osteogenesis imperfecta, there is very limited information published in relation to outcomes. We report the experience at the Royal Children’s Hospital (RCH), Melbourne using Zoledronic acid (ZA), describing outcomes based on the underlying condition for which treatment was given, with the aim of informing future protoc...
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ba0004p30 | (1) | ICCBH2015

Whole-body MR imaging as diagnostic tool in children with hereditary multiple osteochondromas

Staal Heleen , Dremmen Marjolein , Robben Simon , Witlox Adhiambo , van Rhijn Lodewijk

Patients with hereditary multiple osteochondromas (HMO) undergo frequent X-rays to evaluate the growth of the osteochondromas. The conventional radiographs show clear images of the growth of the bony part of the osteochondromas and of the growth direction of the long bones. However the cartilage cap on the osteochondroma nor the cartilage of the nearby epiphysis or the surrounding soft tissue of the osteochondromas is shown. Besides these disadvantages taking frequent radiogra...
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ba0005p33 | Bone biomechanics and quality | ECTS2016

Assessment of changes in collagen associated with advanced glycation end-products in human bone using vibrational spectroscopy

Schmidt Felix Nikolai , Zimmermann Elizabeth Ann , Puschel Klaus , Amling Michael , Vashishth Deepka , Tang Simon , Busse Bjorn

Introduction: Aging, diabetes and other disease conditions are associated with the accumulation of non-enzymatic collagen cross-links (NE-XL) in human tissues. Non-enzymatic cross-links (i.e. advanced glycation end products (AGEs)), occur at the bone collagen level, where they are associated with individuals increased fracture risk caused by bone’s reduced plasticity.Methods: Here, non-destructive Fourier-transform infrared (FTIR) spectroscopy was u...
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Bone Abstracts
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