Bone Abstracts

In the recent years, worldwide the FRAX algorithm is used more extensively to estimate the risk of fragility fractures. Since 2009, the Ukrainian Scientific Medical Centre on Osteoporosis has been extensively using the FRAX algorithm to estimate the fragility fracture risk.The aim of the study was to establish the normative data for the Austrian model of FRAX algorithm. We examined 3405 women aged 40–89. For the statistical analysis of results the S...

According to the literature data, some parameters of the femur (length of axis, length of femoral neck) are independent predictors of hip fractures, but such studies among Ukrainian patients are absent. The purpose of this study was to study age and gender features of some geometric parameters of the upper third of the hip in patients with intra- and extra-articular fractures of the femur.One hundred and seventy-four survey radiographs of the hip joints ...

Osteoarthritis is a complex pathogenesis because diverse factors interact causing a process of deterioration of the cartilage and the subchondral bone. Despite the multifactorial nature of the knee osteoarthritis, it is related to a strong genetic component. Determination of molecular genetic causes of osteoarthritis is an actual problem. There are several approaches to assess the contribution of a candidate gene in the pathogenesis of osteoarthritis. The aim of the study was ...

Osteoporosis has a complex etiology and is considered a multifactorial polygenic disease in which genetic determinants are modulated by hormonal, environmental, and nutritional factors.Polymorphism of the vitamin D receptor gene has been reported to play a major role in variations for genetic regulation of bone mass but its role within various ethnic populations is not clear. Estrogens are known to play an important role in regulating bone homeostasis, t...

Aim: The aim of this study is evaluating of body composition and frequency of sarcopenia in women depending on age.Materials and methods: We have examined 8637 women aged 20–89 years (mean age – 56.7±0.14 years; mean height – 162.5±0.07 cm; mean weight – 73.5±0.16 kg). The patients were divided into two groups depending on age: 20–24 (n=143), 25–29 (n=209), 30–34 (n=271), 35&#15...

The aim of our study was to evaluate the anthropometric characteristics in postmenopausal women depending on appendicular skeletal mass.Materials and methods: We’ve examined 8882 women aged 20–89 years (mean age – 56.7±0.14 years; mean height – 162.5±0.07 cm; mean weight – 73.5±0.16 kg), among them anthropometric measures were performed in 79 postmenopausal women aged 40–82 years (mean age – 63.53±1....

The aim of the study was to evaluate the peculiarities of body composition in postmenopausal women depending on bone mineral density (BMD).Materials and methods: We’ve examined 8882 women aged 20–89 years (mean age – 56.7±0.14 years; mean height – 162.5±0.07 cm; mean weight – 73.5±0.16 kg). Anthropometric measures were performed in 80 postmenopausal women aged 40–82 years (mean age – 63.53±1.08 years...

The aim of the study was to evaluate the role of vitamin D and exercises in correction of age-related skeletal muscle changes in postmenopausal women.Materials and methods: 38 postmenopausal women aged 53–82 years (mean age – 67.00±7.08 yrs) were examined. The women were divided into the following groups: A – control group (n=10), B – women who took an individually-targeted vitamin D therapy (n=11), C – wom...

The aim of the study was to evaluate the appendicular lean mass depending on the dietary protein intake in the Ukrainian postmenopausal women.Materials and methods: The study involved 63 women aged 52–89 years, who, depending on their ages, were divided into groups: 52–59 years (n=9), 60–69 years (n=26), 70–79 years (n=21), 80–89 years (n=7). To assess the dietary habits of women, we used the t...

The aim of the work was to determine the influence of vitamin D deficiency on bone mineral density in schoolchildren.Methods: There were examined 304 children aged 10–18 years. The boys consisted 55.0%. The average age of boys was 12.9±0.2 and girls – 12.4±0.2 years old. Researches included ultrasound densitometry of calcaneus by SAHARA (Hologic), blood chemistry, 25(OH)D and intact parathyroid hormone (iPTH) in plasma were determined...