Bone Abstracts

Traumatic injuries of the bones of various etiologies are accompanied not only a violation of their integrity, but also the development of a system osteopenic syndrome, which causes disorder neurohumoral regulation of the organism and has a negative effect on the structural and functional state of the skeletal tissues of other parts of the skeleton. The information concerning the characteristics of changes in the parameters of growth of molars of the mandible in the literature...

Objectives: The aim of the study was to examine experimentally the possibility smoothing of adverse effects of «fracture syndrome» in the parameters of the growth of the molar row of the mandible with implant in the proximal tibial shaft biogenic hydroxyapatite, saturated with iron at concentrations of 0.05, 0.15 and 0.50%.Methods: For the experiment were collected 168 white mature male rats were divided into four groups: 1st group, animals tha...

Background: The co-occurrence of achondroplasia with Trisomy 21 is extremely rare, with only a handful of published case reports in the literature.Presenting Problem: A baby girl had an antenatal diagnosis of incomplete atrioventricular septal defect (AVSD), and a subsequent postnatal diagnosis of Trisomy 21. At birth she had respiratory distress and required CPAP until 5 days of life. AVSD was confirmed on postnatal ECHO. Phenotypic traits consistent wi...

Aim: Study the features changes of histomorphometric parameters of alveolar ridges in immature rats after thymectomy.Methods: The study was conducted on 120 immature male rats were divided into two groups: 1st group – sham-operated animals, 2nd group – rats with removed of the thymus under mask ether anesthesia (thymectomy). Periods of observation were 7, 15, 30, 90 and 180 days. Rats were euthanized under mask ether anesthesia. For histologica...

Objectives: In the modern society, all individuals are exposed throughout life to a variety of chemicals, which may contribute significantly to the human disease burden. Most of these chemicals are transferred to the fetus in-utero and to the infant via mother’s milk. Until recently, few studies have addressed effects of chemicals on the development of mineralized tissues following exposure during these early stages of life. In this experimental study, we analyse...

Steroids are currently used to improve muscle strength and prolong ambulation in boys with Duchenne muscular dystrophy (DMD) although the effect on bone health is still unclear. The aim of this study was to compare bone strength in healthy children and boys with DMD and investigate the interaction between diminished muscle function, loss of ambulation and high dose oral steroids.Fifty children were studied, 14 healthy boys (HB), 13 boys with DMD who rema...

Objectives: Current guidelines recommend annual assessments of bone densitometry in boys with Duchenne muscular dystrophy (DMD). However, this recommendation is based on the assumption that bone density is a predictor of fractures in this patient group. The aim of this study was to evaluate the relationships between long-term changes in bone density, corticosteroid exposure and mobility with vertebral and long bone fractures.Methods: Twenty-four DMD boys...

Objectives: The aim of this study was establish features changes of organometric parameters of bones in mature male rats after a 60-day inhalation seed toluene.Materials and methods: For the experiment were selected 60 mature male rats were divided into two groups: 1st – intact rats, 2nd group – the rats that every day for 2 months to device for inhalation agents received a one-time inhalation of toluene exposure 4 h in 10 maximum permissible c...

Objectives: The aim of the study was to establish features of macroelemental composition of the dentin in mature male rat’s mandibular incisors with biogenic hydroxyapatite, implanted in the proximal part of tibial shaft.Material and methods: One hundred and twenty-six mature male rats were divided into three groups: 1st group – intact animals, 2nd group – animals with the pit defect applied on the proximal part of tibial shaft (systematic...

Objectives: This study thus was aimed at investigating of ultrastructure of the hipbone biomineral in rats with defect in tibia after 60-day per os administration of sodium benzoate (SB) in various concentrations and mexidol (M).Methods: The experiment involved 280 male thoroughbred rats with initial body weight of 200–210 g. The 1st group (K) comprised animals that received daily per os 1 ml of 0.9% solution of NaCl, the 2nd and t...