Searchable abstracts of presentations at key conferences on calcified tissues

ba0004p178 | (1) | ICCBH2015

The precision of partial image analysis of trabecular bone microarchitecture by high-resolution magnetic resonance imaging in people with childhood-onset bone abnormalities

Chen Suet Ching , Abdalrahaman Naiemh , McComb Christie , Foster John , Ahmed Syed Faisal

Background and objective: High-resolution magnetic resonance imaging (hrMRI) can assess trabecular bone microarchitecture but the number of image slices required for reliable assessment is unclear.Methods: MRI was performed just below the growth plate of the proximal tibia from 20 healthy controls (all female; median age 21 years (range 18–35) and 10 cases (three mals: seven females; median age 19.5 years (range 16–48) with known bone abnormali...

ba0004is11biog | (1) (1) | ICCBH2015

Recent advances in limb lengthening and deformity correction

Herzenberg John

Biographical DetailsDr John Herzenberg graduated from Boston University Medical School and trained at Duke University for Orthopaedics and Toronto Sick Kids for Pediatric Orthopaedics. He specializes in the diagnosis and treatment of adult and pediatric patients with congenital abnormalities, joint contractures, neuromuscular disorders, non-unions, malunions, deformity, and bone defects. ...

ba0006pl1 | (1) | ICCBH2017

Poster List

Poster No. Category Title Author P002 Bone development A 3-year longitudinal study of skeletal effects and growth in children after kidney transplantation <a href="ba...

ba0004p152 | (1) | ICCBH2015

Syphilitic bone disease: a case report

Sukthankar Shaila , Sukthankar Ashish , Wright Neville , Foster Anne , Mughal Zulf

Background: Syphilis remains a great imitator of myriad of clinical diagnosis. Congenital syphilis, though still uncommon, is on the rise once again. Recognition of syphilitic bone disease and its potential impact on growth is important for long term prognosis. We describe our experience of managing a child with congenital syphilis and multisite osteolytic lesions.Presenting problem: A 6 week-old girl presented with a swollen and painful elbow with reduc...

ba0006p088 | (1) | ICCBH2017

Normative data for lateral distal femur bone mineral density in children from 3 to 18 years of age using Lunar Prodigy absorptiometry

Fiscaletti Melissa , Rauch Frank , Foster Bethany , Alos Nathalie

Objectives: Children with compromised weight bearing and limited mobility are particularly at risk for fractures with minimal trauma. Unfortunately, they can also present several obstacles that can impede proper dual X-ray absorptiometry (DXA) scan assessment of whole body or spine bone mineral density (BMD). Since the distal femur is the most common site of fracture in those patients, the lateral distal femur (LDF) represents the site that best addresses the challenges of BMD...

ba0006p175 | (1) | ICCBH2017

Management of Gorham disease in the cervicothoracic spine with mobile gravity traction and Sirolimus

Foster Paul , Mughal M. Zulf , Leong Julian , Jacobs Benjamin

Background: Gorham Disease is a rare condition characterised by massive osteolysis. The pathophysiology is related to angio/lymphatic proliferation within bone. No genetic transmission has been identified and onset occurs in patients of all ages. Surgical fixation of the spine may be unsuccessful due to progressive osteolysis of bone surrounding the metalwork, or of the bone graft.Presenting problem: An 11 year-old boy presented with a 2 year history of ...

ba0001d1.1 | (1) | ECTS2013

For the motion (ECTS)

Campbell John

The incidence of hip fractures is declining in later cohorts of older people but, if the cohort effect is controlled for, the period effect shows a steady increase in incidence. This is almost certainly because we are seeing the survival of an increasingly frail group of older people with comorbidities. The great majority of hip fractures result from falls. There is strong research evidence that falls can be prevented. Proven strength and balance programmes reduce the rate of ...

ba0003d1.1 | (1) | ECTS2014

Debate: there are more benefits than risks associated with HRT in postmenopausal women: for the motion

Stevenson John

Hormone replacement therapy (HRT) comprises estrogen, with or without progestogen addition, given to postmenopausal women. HRT is by far the most effective treatment for the relief of menopausal symptoms such as vasomotor and genito-urinary symptoms. It is as effective as alternative treatments for the prevention of postmenopausal osteoporosis. It increases bone mass, reduces bone turnover, and reduces fracture risk at all the important skeletal sites. It has a beneficial effe...

ba0004is11 | (1) (1) | ICCBH2015

Recent advances in limb lengthening and deformity correction

Herzenberg John

External fixation has been the gold standard for patients who require bone lengthening. This method is accurate and reliable, but can result in significant scarring, superficial infection, and pain. Additionally, the daily care of pin sites, unsightly appearance of the device, and reduced function can be emotionally taxing for both the patient and caregivers. An internal device that lengthens through rotational movement was developed to address some of these issues (ISKD). Alt...

ba0002oc22 | Miscellaneous | ICCBH2013

Prolidase deficient mice are osteoporotic in early life

Foster Sarah , Grabowski Peter , Gallagher Orla , Besio Roberta , Rossi Antonio , Bishop Nick , Forlino Antonella

Background: Proline and hydroxyproline account for ~25% of aminoacids in collagen., Prolidase (peptidase D (EC 3.4.14.9)), cleaves iminodipeptides with a C-terminal proline or hydroxyproline, playing a major role in collagen catabolism. Mice with prolidase deficiency (PD) present with varied phenotypes including reduced size compared to wild-type littermates. We measured structural and mechanical properties of bones in PD mice.Methods: Whole femurs from ...