ba0005p28 | Bone biomechanics and quality | ECTS2016
vom Scheidt Annika
, Krause Matthias
, Puschel Klaus
, Amling Michael
, Busse Bjorn
Although the fracture risk reduction under bisphosphonate treatment in osteoporosis is clinically well established, it remains understudied why the efficacy of bisphosphonate therapy is higher for the prevention of vertebral fractures compared to other fractures.Our aim was to investigate whether anti-resorptive therapy with alendronate would result in different regional variations of structural indices in the vertebral body. We investigated the microstr...