ba0003pp74 | Bone development/growth and fracture repair | ECTS2014
Schnedl Christian
, Bisping Egbert
, Zajic Paul
, Dimai Hans Peter
, Wagner Doris
, Pieber Thomas R
, Fahrleitner-Pammer Astrid
, Amrein Karin
Introduction: Elevated FGF-23 serum levels are induced by hyperphosphatemia and are linked to poor skeletal mineralization and adverse outcomes including vascular calcification and mortality. Recently, it was shown that FGF-23 levels are substantially elevated in acute kidney injury (AKI), and that higher levels in AKI are associated with a greater risk of adverse outcomes.Methods: In 25 vitamin D deficient (25(OH)D <20 ng/ml) critically ill adults w...