Abstract Search

ba0005op18 | Pre-Clinical | ECTS2016

Osteocalcin transgenic mice reveal aspects of the bone/glucose axis, as well as powerful suppression of ectopic osteocalcin protein production

Horsnell Harry , Wee Natalie , Kulkarni Rishikesh , Herzog Herbert , Baldock Paul

see P231....

0 shares

ba0005p231 | Energy metabolism and bone, fat and bone | ECTS2016

Osteocalcin transgenic mice reveal aspects of the bone/glucose axis, as well as powerful suppression of ectopic osteocalcin protein production

Horsnell Harry , Wee Natalie , Kulkarni Rishikesh , Herzog Herbert , Baldock Paul

Rationale: Mice deficient in osteocalcin show an impaired glucose tolerance, however, the exact mechanism involved have yet to be fully elucidated. We aimed to overexpress osteocalcin to determine its effect on glucose homeostasis and explore the signalling pathway involved. We wished to expand upon previous preliminary data suggesting that this pathway involve neuropeptide Y (NPY) signalling.Objective: To analyse the in vivo and in vitro</e...

0 shares

Bone Abstracts

Osteocalcin transgenic mice reveal aspects of the bone/glucose axis, as well as powerful suppression of ectopic osteocalcin protein production

Osteocalcin transgenic mice reveal aspects of the bone/glucose axis, as well as powerful suppression of ectopic osteocalcin protein production

BiosciAbstracts