Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp192 | Genetics | ECTS2014

Genetic determinants of bone mineral density loss in aromatase inhibitors treatment in the B-ABLE Cohort

Rodriguez-Sanz Maria , Garcia-Giralt Natalia , Torres-del Pliego Elisa , Prieto-Alhambra Daniel , Servitja Sonia , Balcells Susana , Mellibovsky Leonardo , Grinberg Daniel , Tusquets Ignasi , Diez-Perez Adolfo , Nogues Xavier

Bone density (BMD) loss is a consequence of aromatase inhibitors (AI) treatment of breast cancer. B-ABLE cohort includes 391 postmenopausal women with early breast cancer starting AI therapy. Participants experienced a 1.98% (95% CI 1.54–2.42% P<0.0001) bone loss at lumbar spine (LS) and 1.24% (95% CI 0.81–1.67% P<0.0001) bone loss at femoral neck (FN) after 1 year on AI therapy and a 3.51% (95% CI 3.00–4.03% P<0.0001) bone...

ba0003pp213 | Osteoporosis: evaluation and imaging | ECTS2014

HIV patients have deteriorated bone material properties assessed by in vivo microindentation

Guerri-Fernandez Robert , Villar-Garcia Judit , Molina-Morant Daniel , Torres-del-Pliego Elisa , Garcia-Giralt Natalia , Vilaplana-Marz Laia , Rodriguez Maria , Mena Alicia Gonzalez , Knobel Hernando , Nogues Xavier , Mellibovsky Lenoardo , Horcajada Juan Pablo , Diez-Perez Adolfo

There is a growing evidence of the association between HIV infection and fracture risk. Independently of its cause (antiretroviral therapy (ART) or HIV), what remains most important is a prompt diagnosis. Although densitometry is the gold standard, sometimes this technique is not as accurate as necessary in clinical practice. A new validated tool for early and more accurate diagnosis is presented.MethodsIn a HIV group of patients, ...