ba0003oc4.5 | Genetics of bone disease | ECTS2014
Shanbhogue Vikram
, Hansen Stinus
, Folkestad Lars
, Brixen Kim
, Beck-Nielsen Signe
Although X-linked hypophosphatemic rickets (XLH) is characterized by hypophosphatemia leading to a generalized mineralization defect with rickets (and/or osteomalacia), densitometric studies point towards a tendency towards an elevated bone mineral density (BMD). The aim of this cross-sectional in vivo study was to assess bone geometry, volumetric BMD (vBMD), microarchitecture and estimated bone strength using high-resolution peripheral quantitative computed tomograph...