Bone Abstracts

Objectives: Nutritional rickets results from the interaction of poor vitamin D status and limited calcium intake. Elevated serum alkaline phosphatase is a marker of impaired mineralization in many forms of rickets. We assessed the reliability of serum alkaline phosphatase in identifying nutritional rickets in calcium-deprived Nigerian children.Methods: We reanalyzed data from a case-control study of Nigerian children with active rickets (cases) and age-,...

Objectives: Nutritional rickets results from the interaction of poor vitamin D status and limited calcium intake. Vitamin D requirements are greater in children with limited intake of calcium. We sought to determine the serum 25-hydroxyvitamin D [25(OH)D] concentration that can prevent rickets in calcium-deprived Nigerian children.Methods: We reanalyzed data from a case-control study of Nigerian children with active rickets (cases) and age-, sex-, and we...