ba0001pp128 | Calciotropic and phosphotropic hormones and mineral metabolism | ECTS2013
Couchman L
, Taylor D
, Krystans B
, Lopez M
, Prakash A
, Sarracino D
, Garces A
, Vogelsang M
, Peterman S
, Vadali G
, Robinson S
, Moniz C
Introduction: Parathyroid hormone (PTH) measurement is of use in i) differential diagnosis of hypercalcaemia and ii) patients with renal impairment at risk of bone disease. PTH immunoassays are complicated by cross-reactivity with truncated (inactive) variant forms, which accumulate in patients with renal impairment. PTH assay variability is a critical governance issue in renal medicine, suggesting an MS-based reference method is required.Aim: To develop...