Bone Abstracts

Objective: To describe changes in the muscle–bone unit, assessed as the ratio of bone mineral content (BMC) to lean body mass (LBM) at skeletal sites during puberty in Indian males and females, after adjusting for age and fat.Methods: Data on arm, leg and total body (less head) BMC, LBM and fat mass (FM) assessed by DXA for 888 apparently healthy children and adolescents (426 females), 5–17 years of age from a cross-sectional study used to gene...

Objective: To study association of VDR gene Fok1 polymorphism locus on bone mass accrual in adolescent girls.Methods: An intervention trial was carried out in 102 girls aged 8–16 years (Pune, India). All girls received 500 mg elemental calcium (daily) and 30 000 IU of vitamin D3 quarterly for 1 year. Outcome variables were measured at baseline and end of the year. Serum levels of ionised calcium (iCa), inorganic phosphorous, parathyroid hor...