Bone Abstracts

Osteoprotegerin gene (OPG) is an important candidate gene of osteoporosis. Association of the OPG polymorphisms and bone mineral density (BMD) have been studied by several research groups, however results are not uniform.The aim of this study was to determine if two polymorphisms in the OPG gene influence bone turnover markers and bone mineral density (BMD) in postmenopausal women and elderly men. A total of 135 patients, aged 41–87 years, were incl...

Urolithiasis is characterized by formation and retention of solid crystals within the urinary tract. There are numerous causes that may lead to urinary stone formation. However, kidney stones are mostly composed of calcium oxalate that predominantly generates free radicals that are toxic to renal tubular cells.The aim of the study is to explore the toxic effect of oxalate to renal epithelial cells and to explore possible effects of antioxidants on its in...