ba0003pp14 | Arthritis and other joint diseases: translational and clinical | ECTS2014
Behra-Marsac Aurelie
, Bonnet Christine
, Mabit Christian
, Coste Cedric
, Preux Pierre-Marie
, Vergne-Salle Pascale
, Dufauret-Lombard Carine
, Treves Richard
, Bertin Philippe
Total hip arthroplasty (THA) is the treatment for severe hip osteoarthritis. It improves the quality of life, pain and patient autonomy. However, a periprosthetic resorption may occur, in 35% of patients after 10 years of the primary surgery requiring implant replacement. Bisphosphonates (BP), inhibitors of bone resorption, represent a potential candidate for modulating periprosthetic bone loss. Randomized controlled trials have also suggested that BP could prevent early...