ba0003pp46 | Bone development/growth and fracture repair | ECTS2014
Haffner-Luntzer Melanie
, Heilmann Aline
, Rapp Anna
, Schinke Thorsten
, Amling Michael
, Ignatius Anita
, Liedert Astrid
One growth factor that potentially plays a role in fracture healing is midkine (Mdk). Mdk is expressed in chondrocytes during bone repair (Ohta et al. 1999) and has been shown to influence bone mass and mechanotransduction (Neunaber et al. 2010, Liedert et al. 2011). The aim of the present study was to evaluate the effects of Mdk-deficiency on bone repair in a standardized mouse femur osteotomy model.Mdk-deficient and wildtype ...