ba0005p249 | Genetics and Epigenetics | ECTS2016
Henaff Carole Le
, Partridge Nicola
, Jehan Frederic
, Geoffroy Valerie
Molecularly characterized epigenetic networks that control bone formation and are altered during aging are necessary to uncover new potential targets for osteoanabolic therapy. Our contribution to the iBONE consortium is to identify osteoanabolic epigenomic regulators by screening which are involved in osteoblast phenotype and differentiation. This study will be done by a 3 step approach including: siRNA screening for epigenomic regulators of osteoblastic differentiation and v...