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ba0001pp201 | Cell biology: osteoblasts and bone formation | ECTS2013

Primary Human Bone Cells treated with Parathyroid Hormone or Dexamethasone show Effects on micro-RNA Expression Patterns Assessed by Second Generation Sequencing

Laxman Navya , Rubin Carl-Johan , Mallmin Hans , Nilsson Olle , Tellgren-Roth Christian , Kindmark Andreas

Introduction: Micro-RNAs (miRNAs) are important post-transcriptional regulators. By binding to complementary RNA strands, they affect mRNA levels and/or mRNA translation. We have previously identified ~90 miRNAs with significant expression levels, with a subset of miRNAs exhibiting interindividual and/or gender differences in expression. In the present project, we have investigated the impact of treatment of parathyroid hormone (PTH) and dexamethasone (DEXA) on global miRNA ex...

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Primary Human Bone Cells treated with Parathyroid Hormone or Dexamethasone show Effects on micro-RNA Expression Patterns Assessed by Second Generation Sequencing

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