Bone Abstracts

The essential micronutrient Selenium (Se) plays an important role for bone formation and homeostasis. This notion is mainly derived from animal experimental studies showing impaired bone development and reduced measures of bone quality in animals on diets with low Se supply. Selenoprotein P (SePP) functions as the central Se storage and transport protein. SePP-knockout mice have a growth deficit. SePP is taken up by a receptor-mediated mechanism. We hypothesize that impaired S...