ba0001pp290 | Muscle, physical activity and bone | ECTS2013
Musson David
, JungJoo Kim
, Callon Karen
, Naot Dorit
, Shim Vickie
, Anderson Iain
, Cornish Jillian
, Chhana Ashika
The musculoskeletal system experiences severe mechanical strain, with repetitive or extreme strains causing significant trauma; the result being an increase in mechanobiological studies evaluating mechanical strain on musculoskeletal cells. Currently, most stretching studies utilise fibronectin-coated cultures, as these enhance cell attachment. However, recent studies suggest that fibronectin increases cell turnover and DNA damage and affects cell differentiation. Furthermore,...