ba0003pp59 | Bone development/growth and fracture repair | ECTS2014
Grgurevic Lovorka
, Erjavec Igor
, Brkljacic Jelena
, Pauk Martina
, Jurin Mladenka
, Popek Irena
, Jankolija Morana
, Verbanac Donatella
, Peric Mihaela
, Oppermann Hermann
, Vukicevic Slobodan
BMP6 is a member of the TGFβ superfamily with a high potential to induce new bone formation. Recently, we discovered that blood coagulum from the patients own blood (WBCD) modified with calcium salts serves as an appropriate autologous carrier for BMPs (OSTEOGROW device). Preclinical experiments indicate that BMP6 is efficacious when used in a significantly lower amounts than BMP2 and BMP7. Besides testing its osteogenic activity, we also tested the influence of the...