Bone Abstracts

Objectives: To define the role of bone morphogenetic proteins (BMP) in human osteochondromas. The expression of bone morphogenetic proteins and their corresponding receptors has not been clarified in osteochondromas. We determined immunohistochemically the localization and distribution of bone morphogenetic proteins 2, 4, 6 and 7, bone morphogenetic protein receptor types 1A, 1B and 2 and the functional effectors phosphorylated Smad proteins 1, 5 and 8 in the cartilaginous cap...