ba0003pp99 | Cancer and bone: basic, translational and clinical | ECTS2014
Luchavova Maria
, Zimovjanova Martina
, Zikan Vit
, Pribylova Jana
, Cabinakova Michaela
, Petruzelka Lubos
Postmenopausal women with early stage hormone-receptor-positive breast cancer (EBC) are standardly treated with aromatase inhibitors (AIs). However, one side-effect of AIs treatment is a decrease in bone mineral density (BMD) and an increased risk of fracture. The objectives of this study were to examine: i) changes in bone formation (N-terminal propeptide of type I procollagen; PINP) and bone resorption (cross-linked C-telopeptides of bone type I collagen; CTX) markers, as we...