Bone Abstracts

Background: Recent data showed that some bone related markers (osteocalcin, 25OHD3) correlate with BMI in the pediatric population. From the other side, obesity in childhood can increase the risk of cardiovascular morbidity and mortality in adulthood. Increased oxidative stress can be one from the causative mechanisms involved in the pathophysiology of almost every complication in obesity. The aim of this study was to determine the relationship between bone turnover markers, n...

Background: Body composition changes during the developmental period and differs in children with idiopathic scoliosis (IS). No large-scale study has been performed to reveal the link between scoliotic deformity and body composition assessed by bioimpedance method (BIA). The study objective was to correlate the extent of scoliotic-curve severity with nutritional status of patients with IS based on standard anthropometrical analysis and BIA.Material and m...

Background: Based on our recent data, nutritional status disturbances (both under- and overweight) can be associated with the severity of scoliotic curve. Objectives: The study objective was to compare two methods for the assessment of nutritional status (routine BMI calculation vs body composition analysis by bioelectrical impedance analyzer (BIA)) in the group of pediatric patients with idiopathic scoliosis (IS).Methods: 317 patients (240 girls/77 boys...

Tricho-rhino-pharyngeal syndrome (TRPS) is a rare genetic disorder, which is characterized by craniofacial and skeletal abnormalities. This report presents three cases of TRPS (two sporadic and one familial). Clinical presentation included typical facial features (pear-shape nose, long flat philtrum, thin upper vermilion border and protruding ears), thin, sparse scalp hair and different skeletal abnormalities with normal mentation. Case 1: 5.5-year-old boy with short stature (...

Background: Tricho-rhino-pharyngeal syndrome (TRPS) is a rare genetic disorder, which is characterized by craniofacial and skeletal abnormalities. Presenting problem: This report presents four cases of TRPS (three sporadic and one familial). Clinical presentation included typical facial features (pear-shape nose, long flat philtrum, thin upper vermilion border, and protruding ears), thin, sparse scalp hair, and different skeletal abnormalities with normal mentation. All of the...

The link between scoliotic deformity and bone metabolism in adolescent idiopathic scoliosis (AIS) has not been well researched. Moreover, the data concerning the cross-talk between leptin level and bone markers in this group of patients are lacking. The objective of this study was to correlate the extent of scoliotic-curve severity with the bone turnover and leptin level in girls with AIS. The study encompassed 77 AIS girls, aged 14.7±2.17 years. Scoliotic curve severity ...

Introduction: Recently published data revealed that bone turnover is related to the body composition in pubertal children and may be impaired in obese adolescents. The aim of the study was to determine the relationship between bone turnover markers, body composition and leptin level in obese children.Material and methods: In 54 obese adolescents (25 boys and 29 girls) in the mean age of 13.96±2.78 years bone turnover markers – osteocalcin (OC),...