Bone Abstracts

Osteoporosis is a growing public health problem. As allies have for preventing physical activity, especially resistance training (RT) and hormone replacement. The aim of this study was to analyze the effect of Raloxifene (RLX) and RT in bone metabolism of rats on their aging period. Wistar rats (14–18 months), sham or ovariectomized (OVX) were treated with RLX (1 mg/kg per day) or saline by gavage and subjected to RT or not. The animals were subjected to RT-oriented pract...

In order to examine metabolic and biophysical parameters arising from obesity, male rats were given to drinking 30% sucrose (p/v) for 8 weeks. During the experimental period, animals in the control group (C) consumed higher amounts of food and water, but the body mass was smaller than the group receiving sucrose (S). In this group, the caloric load given to the animals for eight weeks resulted in increased energy consumption, in glycemia and in plasma leptin and abdominal fat....

The purpose of this study was to analyze the influence of diet supplemented with hydrosoluble soy extract – HSE in bone mass of male and healthy Wistar rats. Sixteen (16) 30 days old animals were kept in controlled conditions with light/dark cicle and fed with commercial food and filtered water. Randomized into two groups: control group received 500 ml of water and 300 g of food, daily; supplemented group S, in addition of water and food, they also received 500 ml of soy ...

The exposition of shift workers to light at night supresses the melatonin (ME) production. ME supression may contribute to the development of osteoporosis, which can be prevented and treated by resistance exercise (RE). This study evaluated the effect of ME release supression by pineal gland (pinealectomy) and the RE on rats tibiae morphology, mineral quantification and mechanical parameters. The project was approved by the local ethics committee (protocol 2014-00939). Fourty ...

Osteoporosis is a multifactorial disease that represents an increase public health problem, given the impact on functional independence and quality of life. Among the favoring factors to the imbalance in bone cell activity, the hypoestrogenism is primordial. Strength training (ST) proves to be effective because of its ability to stimulate estrogen receptor independent of ligand. In this study, we analyzed the action of ST on bone quality of rats during the aging. For this stud...

The effects of neonatal thymectomy, at 3 days of age, on skeletal sexual dimorphism and bone quality during the development were examined in male and female Wistar rats. Rats were euthanized at 20, 40, or 120 postnatal days and femurs were collected. The Biomechanical compression test was used to evaluate bone breaking strength, energy-to-fracture, and extrinsic stiffness. During the prepubertal period, the neonatal thymectomy increases extrinsic stiffness of bone tissue signi...