ba0002p22 | (1) | ICCBH2013
Tam Elisa M S
, Yu Fiona W P
, Hung Vivian W Y
, Liu Zhen
, Lam Tsz-Ping
, Liu King Lok
, Ng Bobby K W
, Lee Simon K M
, Qiu Yong
, Cheng Jack C Y
Objectives: Low bone mass in adolescent idiopathic scoliosis (AIS) has been well reported, however the etiologies of the disease and this abnormal phenotype were still unknown. Leptin have profound effects on bone metabolism and skeletal growth, and was speculated to play a role in the etiopathogenesis of AIS. The objective of this study was to investigate the bone quality in AIS and its association with leptin and soluble leptin receptor (sOB-R).Methods...