Bone Abstracts

Introduction: Intracellular fat within muscle and visceral tissue has been suggested to adversely influence bone development.Design: We aimed to compare associations between intramuscular and subcutaneous fat and cortical bone outcomes in young adults, in cross-sectional analyses based on the Avon Longitudinal Study of Parents and Children.Method: Data were collected from a research clinic conducted at 17 years of age. Intramuscula...

Objectives: Studies indicate that later puberty is associated with lower bone mineral density (BMD) in childhood. Less is known about effects of puberty timing on long-term bone accrual. We examined association between age at puberty and BMD accrual rate from 10 to 25 years.Methods: This was a prospective birth cohort of healthy largely European people born in southwest England in 1991–1992 and regularly follow-up from birth to mean age 25 years. Ag...

Hip development is influenced by mechanical loading during fetal movement by joint and reaction forces equivalent to several times bodyweight. These forces increase with fetal size and gestation length, and are lower in oligohydramnios and breech presentation which are both risk factors for developmental hip disorders. However, associations between indicators of prenatal mechanical loading and hip shape in later life remain unexplored. We therefore examined associations betwee...