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ba0001pp70 | Bone development/growth and fracture repair | ECTS2013

A casein-based diet leads to a better bone status than a soy protein-based diet during moderate protein restriction in growing mice

Rouy Emilien , Laroche Norbert , Blachier Francois , Tome Daniel , Vico Laurence , Blais Anne

This study aims at determining if casein would lead to a better bone status than soy in the context of a moderate protein restriction (6% of total energy intake) in growing mice.Ten-week-old female Balb/C mice were divided in four groups of 15 animals. Two groups received 6% of their energy intake as protein, one as casein and the other as soy protein. The third group was a normal-protein control receiving 20% soy protein. The last group (positive contro...

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ba0005p31 | Bone biomechanics and quality | ECTS2016

Site specific bone loss induced by spaceflight in mice: a multiscale evaluation of trabecular and cortical structure and quality

Gerbaix Maude , Gnyubkin Vasily , Delphine Farlay , Helene Follet , Patrick Ammann , Cecile Olivier , Francoise Peyrin , Norbert Laroche , Boris Shenkman , Guillemette Gauquelin-Koch , Laurence Vico

Intrinsic quality, micro and nano structure of bone after 1 month of spaceflight and during 1 week of recovery had never been investigated. The aim was to explore these properties in appendicular and axial skeleton of mature mice.Ten C57/Bl6 male mice flew on the 30-day space Russian BION-M1 high-orbit satellite mission (Biomedical Ethics Commission of IBMP, n°319). Five were euthanized 12 h after landing, the others 8 days later. A ground control g...

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Bone Abstracts

A casein-based diet leads to a better bone status than a soy protein-based diet during moderate protein restriction in growing mice

Site specific bone loss induced by spaceflight in mice: a multiscale evaluation of trabecular and cortical structure and quality

BiosciAbstracts