ba0001pp267 | Genetics | ECTS2013
Trummer Olivia
, Thurner Eva
, Langsenlehner Tanja
, Langsenlehner Uwe
, Krenn-Pilko Sabine
, Marz Winfried
, Pieber Thomas
, Obermayer-Pietsch Barbara
, Renner Wilfried
Preclinical and epidemiologic data suggest that vitamin D deficiency may play a role in the pathogenesis and progression of prostate cancer. Based on recently reported genetic determinants of vitamin D insufficiency we investigated a functional T>G single nucleotide polymorphism (SNP) in the group-specific component (GC) gene for its association with 25-hydroxy (25-OH) vitamin D and 1.25 dihydroxy (1.25-OH) vitamin D levels and further to test a possible association with m...