Abstract Search

ba0003oc1.2 | Phosphate metabolism, fracture repair and osteoarthritis | ECTS2014

Study of Hyp or Phex null male fetuses reveals that eightfold increased FGF23 does not alter fetal–placental phosphorus homeostasis or prenatal bone formation and mineralization

Ma Yue , Kirby Beth J. , Kovacs Christopher S.

Fibroblast growth factor-23 (FGF23) controls serum phosphorus by acting on the kidneys to excrete phosphorus and reduce calcitriol. These actions are well established in adults and children, but whether FGF23 regulates fetal phosphorus metabolism is unknown. We used X-linked Hyp or Phex null male fetuses to study the effect of excess FGF23 on fetal phosphorus metabolism. Phex+/− females and WT males were mated to generate WT, Phe...

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ba0005op22 | Clinical (1) | ECTS2016

Trabecular (spine) bone density increases significantly in the first six months after weaning (factors affecting bone formation after breastfeeding pilot study (FABB-Pilot))

Cooke-Hubley Sandra , Mugford Gerry , Valcour James , Wahl Michael , Woodrow Janine , Adachi J. D. , Kovacs Christopher S.

see P75....

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ba0005p88 | Calciotropic and phosphotropic hormones and mineral metabolism | ECTS2016

Trabecular (Spine) bone density increases significantly in the first 6 months after weaning (Factors Affecting Bone Formation After Breastfeeding Pilot Study (FABB-Pilot))

Cooke-Hubley Sandra , Mugford Gerry , Valcour James , Wahl Michael , Woodrow Janine , Adachi J D , Kovacs Christopher S

Breastfeeding women resorb trabecular bone to supply much of the calcium content of milk. Few studies have examined the speed and extent of BMD recovery after weaning, or the factors that predict a greater post-lactation increase in BMD. We hypothesize that weight-bearing, nutrition, hormones, and other factors facilitate bone formation after lactation.The aims of the Factors Affecting Bone Formation After Breastfeeding Pilot Study (FABB-Pilot) were to d...

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ba0005p360 | Osteoporosis: pathophysiology and epidemiology | ECTS2016

Warfarin use and changes in bone mineral density in the population-based canadian multicentre osteoporosis study (CaMos)

Vaninetti Nadine , Kirkland Susan , Thompson Kara , Theriault Chris , Prior Jerilynn , Kovacs Christopher , Adachi Rick , Towheed Tanveer , Leslie William , Davison K Shawn , Morin Suzanne , Goltzman David , Kaiser Stephanie

Background: Osteocalcin has an important role in bone metabolism. Uncarboxylated osteocalcin predicts risk for hip fracture and lower bone mineral density (BMD). Warfarin inhibits carboxylation of osteocalcin, providing a mechanistic link between warfarin and impaired bone metabolism. Studies examining the relationship between warfarin use and BMD have been inconsistent. The goal of this study was to further characterize this relationship.Population: CaM...

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Bone Abstracts

Study of Hyp or Phex null male fetuses reveals that eightfold increased FGF23 does not alter fetal–placental phosphorus homeostasis or prenatal bone formation and mineralization

Trabecular (spine) bone density increases significantly in the first six months after weaning (factors affecting bone formation after breastfeeding pilot study (FABB-Pilot))

Trabecular (Spine) bone density increases significantly in the first 6 months after weaning (Factors Affecting Bone Formation After Breastfeeding Pilot Study (FABB-Pilot))

Warfarin use and changes in bone mineral density in the population-based canadian multicentre osteoporosis study (CaMos)

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