Bone Abstracts

Objectives: Weight loss therapy is the principal non-pharmacological method for prevention and treatment of simple obesity in childhood. This intervention may influence bone metabolism in children, but this phenomenon is not well understood. The aim of this study was to assess the changes in body composition and in the profile of bone markers after weight loss in obese prepubertal children.Methods: We determined serum BALP (bone alkaline phosphatase), CT...

Introduction: Obesity is the direct cause of a number of immediate problems during childhood. Among them the high prevalence of fractures and joint problems in obese children was observed. Leptin may influence the development and bone remodeling in children, but this phenomenon is not well understood. Therefore, we studied the relationships between leptin and bone turnover markers, growth factors and anthropometric parameters in obese children.Descriptio...