ba0003pp300 | Osteoporosis: treatment | ECTS2014
Ornstrup Marie Juul
, Harslof Torben
, Kjaer Thomas Nordstrom
, Paulsen Soren Kildeberg
, Langdahl Bente Lomholt
, Pedersen Steen Bonlokke
Background: Resveratrol (RSV) is a natural polyphenolic compound, found in fx grapes, which possesses anti-inflammatory properties. RSV inhibits osteoclast activity and promotes osteoblastogenesis in vitro. Furthermore, RSV protects against bone loss after ovarectomy and immobilization in animal models. RSV treatment of obese men for 4 weeks resulted in an increase in bone specific alkaline phosphatase (BAP).Hypothesis: Low-grade inflammation is...