Bone Abstracts

As a bone-derived hormone that regulates phosphate homeostasis and renal 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] production, fibroblast growth factor (FGF)-23 has been postulated to indirectly control calcium and bone metabolism by modulating the levels of phosphate and 1,25(OH)2D3. However, the presence of FGF receptor-1 (FGFR-1) proteins in the intestinal epithelial cells suggests that the intestine may directly respond t...