Bone Abstracts

The therapy of osteoporosis in patients with end organ failure and after the transplantation (Tx) becomes more frequent problem with the better patients and graft survival rates. Moreover some of these patients have impaired renal function and therefore cannot use bisphosphonates. The supplementation therapy with calcium and/or vitamin D is frequently not sufficient to improve bone mass. The possible innovative therapy is Denosumab (Prolia inj.) - MAB to RANK, which is not con...

Objectives: Simultaneous pancreas kidney transplantation (SPKT) is a standard treatment option for adults with long-lasting (usually adolescence onset) type 1 diabetes (T1D) and concurrent renal failure. Despite the need for life-long immunosuppressive therapy the patients achieve better glycemic control, normalized renal function and an improved quality of life. Whether metabolic improvement is also reflected in the skeleton is not yet clear.Methods: Pa...